Fluoroiodomethane

Fluoroiodomethane
IUPAC name Fluoroiodomethane
Other names Fluoro-iodo-methane, Fluoromethyl iodide
Identifiers
CAS number	373-53-5
ChemSpider	10329326 Y
Jmol-3D images	Image 1
SMILES FCI
InChI InChI=1S/CH2FI/c2-1-3/h1H2 Y Key: XGVXNTVBGYLJIR-UHFFFAOYSA-N Y InChI=1/CH2FI/c2-1-3/h1H2
Properties
Molecular formula	CH2FI
Molar mass	159.93 g/mol
Boiling point	53.4 °C
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Fluoroiodomethane is a mixed halomethane, more exactly fluoroiodocarbon (FIC).

Fluoroiodomethane can be prepared from iodoacetic acid.^[1]

Its isotopomer [¹⁸F]fluoroiodomethane (PubChem 451313) is a synthetic precursor for fluoromethylation of radiopharmaceuticals.

Also proposal of its use as a safe high-performance foam blowing agent exists.^[2]

Notes

References

• Zheng L.; Berridge M. S. (January 2000). "Synthesis of [¹⁸F]fluoromethyl iodide, a synthetic precursor for fluoromethylation of radiopharmaceuticals". Applied Radiation and Isotopes 52 (1): 55–61(7). doi:10.1016/S0969-8043(99)00061-5. PMID 10670923. Retrieved 2007-06-29. 
• Chin F. T., Morse Ch. L., Shetty H. U., Pike V. W. (December 2005). "Automated radiosynthesis of [18F]SPA-RQ for imaging human brain NK1 receptors with PET". Journal of Labelled Compounds and Radiopharmaceuticals 49 (1): 17–31(15). doi:10.1002/jlcr.1016. Retrieved 2007-06-29. 
• Tedder, J. M.; Sloan, J. P.; Walton, J. C. (1975). "Free Radical Addition to Olefins, Part XVII. Addition of Fluoroiodomethane to Fluoroethylenes". Journal of the Chemical Society: 1846–1850.