Flubendazole

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Flubendazole

Systematic (IUPAC) name
Methyl N-[6-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate
Clinical data
AHFS/Drugs.com	International Drug Names
Legal status	?
Identifiers
CAS number	31430-15-6^Y
ATC code	P02CA05 QP52AC12
PubChem	CID 35802
UNII	R8M46911LR^N
KEGG	D04200^Y
ChEBI	CHEBI:77095
ChEMBL	CHEMBL145946^N
Chemical data
Formula	C₁₆H₁₂F N₃O₃
Mol. mass	313.28 g/mol
N (what is this?) (verify)

Flubendazole is an anthelmintic. Its brand name is Flutelmium which is a paste manufactured by Janssen Pharmaceutica N.V. used by veterinarians for protection against internal parasites and worms in dogs and cats. Other brand names are Flubenol, Biovermin, and Flumoxal.^[1]

It is also available for human use to treat worm infections. It is available OTC (without prescription) in Europe.

References

↑ US Patent 5824336 - Chewable flubendazole tablets for companion animals

Antiparasitics – Anthelmintics (P02) and Endectocides (QP54)

Antiplatyhelmintic agents

Antitrematodals
(schistosomicides)

Binds tubulin	benzimidazole Triclabendazole^#

AI	phosphonic acid Metrifonate

Other/unknown	quinoline Praziquantel^# Oxamniquine^# phenol Bithionol thiazole Niridazole arylsulfonate Stibophen

Anticestodals
(taeniacides)

Binds tubulin	benzimidazole Albendazole^#

Other/unknown	salicylanilide Niclosamide^# aminoacridine Quinacrine butyrophenone Desaspidin chlorophenol Dichlorophen

Antinematodal agents
(including
macrofilaricides)

Binds tubulin	benzimidazole Mebendazole^# Albendazole^# Thiabendazole Fenbendazole Ciclobendazole Flubendazole

Glutamate-gated chloride channel, GABA receptor	avermectins Abamectin Doramectin Emamectin Ivermectin Selamectin milbemycins Moxidectin Milbemycin oxime

NMDA	tetrahydropyrimidine Pyrantel^# Pyrantel pamoate Oxantel

Other/unknown	piperazine Piperazine Diethylcarbamazine^# thiazole Levamisole^‡ quinolinium Pyrvinium benzylammonium Bephenium naphthalenesulfonate Suramin^# Tribendimidine

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

M: IFT

helm, arth (acar)

helm, arth (lice), zoon

helm, arth

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