Flabellaria

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Flabellaria
Scientific classification
Kingdom: Plantae
(unranked): Angiosperms
(unranked): Eudicots
(unranked): Rosids
Order: Malpighiales
Family: Malpighiaceae
Genus: Flabellaria
Cav.
Species
  • Flabellaria paniculata Cav.

Flabellaria is a genus in the Malpighiaceae, a family of about 75 genera of flowering plants in the order Malpighiales. Flabellaria includes one variable species, F. paniculata, which is widely distributed in equatorial Africa in thickets, woodlands, and forests, especially along rivers.

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Phytochemical and antibacterial studies of the leaf extracts of Flabelleria paniculata cav, have been investigated [1]. Antibacterial activity was investigated using Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Klebsiella pneumoniae. Methanol extract of F. paniculata was fractionated into petroleum ether, chloroform and aqueous layers successively. Pet. Ether and aqueous fractions were found inactive. At 10mg/ml chloroform extract produced zone of inhibition of 3mm (S. aureus), 2mm (Ps. aeruginosa), 2mm (E. coli) and 3mm (K. pneumoniae). Chloroform extract showed MIC values of 1 .75 mg/ml and 2mg/ml for Ps. aeruginosa and S. aureus respectively. Saponins, cardenolides, alkaloid and tannins were detected in the leaf. In a follow up study to an initial antibacterial study on the methanol leaf extract, Olugbuyiro et al. have reported [2,3] the anti-infective and wound healing effect of the chloroform and aqueous fractions of F. paniculata on wounds inoculated with S. aureus and P. aeruginosa. The findings revealed that chloroform fraction exhibited significant wound healing potency (p < 0.05) as compared with controls. The test drug achieved 100% wound contraction on day 14 in non-infected group, on day 16 in Staphylococcus aureus infected group and on day 18 in Pseudomonas aeruginosa group. Chloroform extract of Flabellaria paniculata has proved to be a potential anti-infective and wound healing agent. Its in vitro antibacterial and in vivo wound healing activities are in good agreement with the local medicinal use of the plant for skin diseases and sores.

Notes 1 Λ Abo,2004, p35. 2 Λ Abo, 2004, p85. 3 Λ Olugbuyiro, 2010,p786. References •Abo, K.A., Olugbuyiro, J.A.O. (2004) Phytochemical and antibacterial studies of extracts of Flabellaria paniculata. African Journal of Biomedical Research 7(1):35-36. •Abo, K.A., Olugbuyiro ,J.A.O., Famakinde, S.A. (2004) Anti-infective and wound healing properties of Flabellaria paniculata 1. African journal of Biomedical Research 7 (2): 85-87. •Olugbuyiro, J.A.O., Abo, K.A., Leigh, O.O. (2010) Wound healing effect Of Flabellaria paniculata leaf extracts Journal of Ethnopharmacology 127: 786-788.

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