Fenamic acid

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Fenamic acid
IUPAC name

2-(phenylamino)benzoic acid

Other names

N-phenylanthranilic acid

Identifiers
CAS number 91-40-7 YesY
PubChem 4386
ChEBI CHEBI:34756 N
ChEMBL CHEMBL23832 N
Jmol-3D images Image 1
Properties
Molecular formula C13H11NO2
Molar mass 213.23 g/mol
 N (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Fenamic acid is a molecule which serves as a parent structure for several non-steroidal anti-inflammatory drugs, including mefenamic acid, tolfenamic acid, flufenamic acid, and meclofenamic acid.

This compound may be synthesized by the reaction of 2-chlorobenzoic acid and aniline, with base and copper oxide catalyst in the Goldberg reaction.[1]

The self-condensation of fenamic acid yields acridone.[1]

References

  1. ↑ 1.0 1.1 C. F. H. Allen and G. H. W. McKee (1943), "Acridone", Org. Synth. ; Coll. Vol. 2: 15 
Non-steroidal anti-inflammatory drugs (NSAIDs) (primarily M01A and M02A, also N02BA)
Pyrazolidines
Salicylates
Acetic acid derivatives
and related substances
Oxicams
Propionic acid derivatives
(profens)
N-Arylanthranilic acids
(fenamates)
Coxibs
Other
Items listed in bold indicate initially developed compounds of specific groups. †Withdrawn drugs. ‡Veterinary use medications.

M: MUS, DF+DRCT

anat (h/n, u, t/d, a/p, l)/phys/devp/hist

noco (m, s, c)/cong (d)/tumr, sysi/epon, injr

proc, drug (M1A/3)

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