Etidocaine

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Etidocaine

Systematic (IUPAC) name
N-(2,6-dimethylphenyl)- 2-(ethyl(propyl)amino)butanamide
Clinical data
Trade names	Duranest
AHFS/Drugs.com	Micromedex Detailed Consumer Information
MedlinePlus	a603026
Pregnancy cat.	B1 (AU) B (US)
Legal status	℞-only (US)
Routes	Parenteral
Pharmacokinetic data
Bioavailability	n/a
Metabolism	Hepatic
Half-life	2.5 hours
Excretion	Renal
Identifiers
CAS number	36637-18-0^N
ATC code	N01BB07
PubChem	CID 37497
IUPHAR ligand	2621
DrugBank	n/a
ChemSpider	34400^Y
UNII	I6CQM0F31V^Y
KEGG	D04095^Y
ChEBI	CHEBI:4904^Y
ChEMBL	CHEMBL492^Y
Chemical data
Formula	C₁₇H₂₈N₂O
Mol. mass	276.42 g/mol
SMILES O=C(Nc1c(C)cccc1C)C(CC)N(CC)CCC
InChI InChI=1S/C17H28N2O/c1-6-12-19(8-3)15(7-2)17(20)18-16-13(4)10-9-11-14(16)5/h9-11,15H,6-8,12H2,1-5H3,(H,18,20)^Y Key:VTUSIVBDOCDNHS-UHFFFAOYSA-N^Y
N (what is this?) (verify)

Etidocaine, marketed under the trade name Duranest, is a local anesthetic given by injection during surgical procedures and labor and delivery. Etidocaine has a long duration of activity, and the main disadvantage of using during dentistry is increased bleeding during surgery.^[1]

References

↑ Sisk, A. L. (1992). "Long-acting local anesthetics in dentistry". Anesthesia progress 39 (3): 53–60. PMC 2148750. PMID 1308373.

External links

Duranest (RxList)

Anesthetics: Local anesthetics - primarily sodium channel blockers (N01B)

Esters

Esters of aminobenzoic acid	Amylocaine Benzocaine Butacaine Butamben Chloroprocaine Dimethocaine Meprylcaine Metabutethamine Metabutoxycaine Orthocaine Propoxycaine Procaine (Novocaine) Proxymetacaine Risocaine Tetracaine

Esters of benzoic acid	3-(p-Fluorobenzoyloxy)tropane Cocaine Cyclomethycaine Hexylcaine Piperocaine

Amides

Articaine
Bupivacaine # /Levobupivacaine/Ropivacaine
Butanilicaine
Carticaine
Dibucaine
Etidocaine
Lidocaine #
Mepivacaine
Prilocaine
Trimecaine

Combinations

Anesthetic/anesthetic - Lidocaine/prilocaine

Anesthetic/vasoconstrictor - Iontocaine

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

M: PNS

anat (h/r/t/c/b/l/s/a)/phys (r)/devp/prot/nttr/nttm/ntrp

noco/auto/cong/tumr, sysi/epon, injr

proc, drug (N1B)

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