Ethacizine
From Wikipedia, the free encyclopedia
Systematic (IUPAC) name | |
---|---|
ethyl N-[10-[3-(diethylamino)propanoyl]phenothiazin-2-yl]carbamate | |
Clinical data | |
Trade names | Ethacizin |
AHFS/Drugs.com | International Drug Names |
Legal status | Prescription only (RU) |
Pharmacokinetic data | |
Bioavailability | ~40% (oral)[1] |
Protein binding | 90% |
Metabolism | Extensive hepatic |
Half-life | 2.5 hours |
Identifiers | |
CAS number | 33414-33-4 |
ATC code | C01BC09 |
PubChem | CID 107841 |
ChemSpider | 96982 |
UNII | FE5SPV1Z6G |
Chemical data | |
Formula | C22H27N3O3S |
Mol. mass | 413.54 g/mol |
SMILES
| |
| |
Ethacizine (ethacyzine) is a class Ic antiarrhythmic agent, related to moracizine. It is used in Russia and some other CIS countries for the treatment of severe and/or refractory ventricular and supraventricular arrhythmias, especially those accompanied by organic heart disease. It is also indicated as a treatment of refractory tachycardia associated with Wolff–Parkinson–White syndrome.[1]
It is manufactured under the brand name Ethacizin (Этацизин) by Olainfarm.[2]
References
- ↑ 1.0 1.1 "Этацизин (Ethacyzin) Prescribing Information. VIDAL Drug Compendium" (in Russian). Retrieved 5 February 2014.
- ↑ "Этацизин—4DOKTOR.RU Drug Information Handbook" (in Russian). Retrieved 5 February 2014.
|
This article is issued from Wikipedia. The text is available under the Creative Commons Attribution/Share Alike; additional terms may apply for the media files.