Etaqualone
From Wikipedia, the free encyclopedia
Systematic (IUPAC) name | |
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3-(2-ethylphenyl)-2-methyl-quinazolin-4-one | |
Clinical data | |
Legal status | Unscheduled |
Identifiers | |
CAS number | 7432-25-9 |
ATC code | None |
PubChem | CID 23914 |
ChemSpider | 22357 |
UNII | HFS3HB32J7 |
ChEMBL | CHEMBL2104633 |
Chemical data | |
Formula | C17H16N2O |
Mol. mass | 264.322 |
SMILES
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Etaqualone (Aolan, Athinazone, Ethinazone[1]) is an analogue of methaqualone which was developed in the 1960s[2][3] and marketed mainly in France and some other European countries. It has sedative, hypnotic, muscle relaxant and central nervous system depressant properties, and was used for the treatment of insomnia.
See also
- Methaqualone
- Methylmethaqualone
- Mecloqualone
- Mebroqualone
- Cloroqualone
- Diproqualone
- Afloqualone
- Nitromethaqualone
- SL-164
References
- ↑ Pflegel, P.; Wagner, G. (1967). "(title in German)" [On the Polarography of 2-Methyl-3-(2-methylphenyl)-3,4-dihydroquinazolinone-(4) (methaqualone, Dormutil) and 2-methyl-3-(2-ethylphenyl-3,4-dihydroquinazolinone-(4) (ethinazone, Aolan). 5. Polarography of Heterocyclic Compounds]. Die Pharmazie (in German) 22 (11): 643–650. PMID 5619478.
- ↑ GB patent 936902, "Quinazolinone Derivatives", issued 1963-09-18, assigned to Beiersdorf
- ↑ Parmar, S. S.; Kishor, K.; Seth, P. K.; Arora, R. C. (1969). "Role of Alkyl Substitution in 2,3-Disubstituted and 3-Substituted 4-Quinazolones on the Inhibition of Pyruvic Acid Oxidation". Journal of Medical Chemistry 12 (1): 138–141. doi:10.1021/jm00301a035. PMID 4303122.
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