Estradiol undecylate
From Wikipedia, the free encyclopedia
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| Systematic (IUPAC) name | |
| (17β)-3-hydroxyestra-1,3,5(10)-trien-17-yl undecanoate | |
| Clinical data | |
| Legal status | ℞ Prescription only |
| Routes | IM[1] |
| Identifiers | |
| CAS number | 3571-53-7 |
| ATC code | None |
| PubChem | CID 19135 |
| ChemSpider | 18055 |
| Synonyms | 17β-Estradiol-17-undecanoate |
| Chemical data | |
| Formula | C29H44O3 |
| Mol. mass | 440.658 g/mol |
| SMILES
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Estradiol undecylate (INN, USAN; brand names Delestrec, Depogin, Primogyn Depot, Progynon Depot, others) is a synthetic ester, specifically the 17-undecanoyl ester, of the natural estrogen, estradiol.[2][3] It has been in use since the mid-1950s,[4] and was formerly often used to treat prostate cancer, but has since largely been superseded by newer agents with fewer adverse effects for this indication.[1][5]
See also
References
- ↑ 1.0 1.1 Christoph Zink (1 January 1988). Dictionary of Obstetrics and Gynecology. Walter de Gruyter. p. 85. ISBN 978-3-11-085727-6. Retrieved 20 May 2012.
- ↑ A. D. Roberts (1991). Dictionary of Steroids: Chemical Data, Structures, and Bibliographies. CRC Press. p. 415. ISBN 978-0-412-27060-4. Retrieved 20 May 2012.
- ↑ Index Nominum 2000: International Drug Directory. Taylor & Francis US. 2000. p. 405. ISBN 978-3-88763-075-1. Retrieved 20 May 2012.
- ↑ WIED GL (January 1954). "[Estradiol valerate and estradiol undecylate, two new estrogens with prolonged action; comparison with estradiol benzoate]". Geburtshilfe Und Frauenheilkunde (in Undetermined) 14 (1): 45–52. PMID 13142295.
- ↑ Ernst Mutschler; Hartmut Derendorf (1995). Drug Actions: Basic Principles and Therapeutic Aspects. CRC Press. p. 609. ISBN 978-0-8493-7774-7. Retrieved 30 January 2013.
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