Elephantopin

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Elephantopin
Identifiers
CAS number 13017-11-3 YesY
PubChem 264743
ChEMBL CHEMBL400927 N
Jmol-3D images {{#if:O=C1C(C[C@H](OC(C(C)=C)=O)[C@@]23[H])=CC(O1)C[C@]4(C)[C@H](O4)[C@@]3([H])OC(C2=C)=O|Image 1
Properties
Molecular formula C19H20O7
Molar mass 360.36 g mol−1
 N (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Elephantopin is a natural chemical compound extracted from the Elephantopus elatus plant of the genus Elephantopus, family Compositae. It is a sesquiterpene lactone with a germacranolide skeleton, containing two lactone rings and an epoxide functional group.[1]

It has been shown to have an antitumor activity.[2]

References

  1. Kupchan, S. Morris; Aynehchi, Y.; Cassady, John M.; McPhail, A. T.; Sim, G. A.; Shnoes, H. K.; Burlingame, A. L. (1966). "The isolation and structural elucidation of 2 novel sesquiterpenoid tumor inhibitors from Elephantopus elatus". Journal of the American Chemical Society 88 (15): 3674–3676. doi:10.1021/ja00967a056. 
  2. Rajkapoor, B; Jayakar B; Anandan R. (Jan-Feb 2002). "Antitumor activity of elephantopus scaber linn against dalton's ascitis lymphoma" (Abstract at IndMED). Indian Journal of Pharmaceutical Sciences 64 (1): 71–3. Retrieved 3 December 2009. 


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