Elephantopin
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Elephantopin | ||
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IUPAC name (1aR,8S,8aR,11aS,11bR)-1a-Methyl-9-methylene-5,10-dioxo-2,3,5,7,8,8a,9,10,11a,11b-decahydro-1aH-3,6-(metheno)furo[2,3-f]oxireno[2,3-d][1]oxacycloundecin-8-yl methacrylate | ||
Identifiers | ||
CAS number | 13017-11-3 | |
PubChem | 264743 | |
ChEMBL | CHEMBL400927 | |
Jmol-3D images | {{#if:O=C1C(C[C@H](OC(C(C)=C)=O)[C@@]23[H])=CC(O1)C[C@]4(C)[C@H](O4)[C@@]3([H])OC(C2=C)=O|Image 1 | |
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Properties | ||
Molecular formula | C19H20O7 | |
Molar mass | 360.36 g mol−1 | |
(verify) (what is: / ?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa) | ||
Infobox references | ||
Elephantopin is a natural chemical compound extracted from the Elephantopus elatus plant of the genus Elephantopus, family Compositae. It is a sesquiterpene lactone with a germacranolide skeleton, containing two lactone rings and an epoxide functional group.[1]
It has been shown to have an antitumor activity.[2]
References
- ↑ Kupchan, S. Morris; Aynehchi, Y.; Cassady, John M.; McPhail, A. T.; Sim, G. A.; Shnoes, H. K.; Burlingame, A. L. (1966). "The isolation and structural elucidation of 2 novel sesquiterpenoid tumor inhibitors from Elephantopus elatus". Journal of the American Chemical Society 88 (15): 3674–3676. doi:10.1021/ja00967a056.
- ↑ Rajkapoor, B; Jayakar B; Anandan R. (Jan-Feb 2002). "Antitumor activity of elephantopus scaber linn against dalton's ascitis lymphoma" (Abstract at IndMED). Indian Journal of Pharmaceutical Sciences 64 (1): 71–3. Retrieved 3 December 2009.
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