Electron-detachment dissociation

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Electron-detachment dissociation (EDD) is a method for fragmenting anionic species in mass spectrometry.^[1]

It serves as a negative counter mode to Electron capture dissociation.

Negatively charged ions are activated by irradiation with electrons of moderate kinetic energy. The result is ejection of electrons from the parent ionic molecule, which causes dissociation via recombination.

References

↑ Budnik BA, Haselmann KF, Zubarev RA (2001). "Electron detachment dissociation of peptide di-anions: an electron–hole recombination phenomenon". Chemical Physics Letters 342 (3-4): 299–302. doi:10.1016/S0009-2614(01)00501-2.

v t e Mass spectrometry

Mass m/z Mass spectrum MS software Acronyms

Ion source	APCI APLI CI DAPPI DART DESI DIOS EESI EI ESI FAB FD GD IA ICP LAESI MALDI MIP SS SSI TI TS

Mass analyzer	Sector Wien filter Time-of-flight Quadrupole mass filter Quadrupole ion trap FT-ICR Orbitrap

Detector	Electron multiplier Microchannel plate detector Daly detector Faraday cup Langmuir–Taylor detector

MS combination	MS/MS QqQ Hybrid MS GC/MS LC/MS IMS/MS

Fragmentation	BIRD CID ECD EDD ETD HCD IRMPD NETD SID

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