ERF (gene)
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| Ets2 repressor factor | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | ERF; PE-2; PE2 | ||||||||||||
| External IDs | OMIM: 611888 MGI: 109637 HomoloGene: 68516 GeneCards: ERF Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 2077 | 13875 | |||||||||||
| Ensembl | ENSG00000105722 | ENSMUSG00000040857 | |||||||||||
| UniProt | P50548 | P70459 | |||||||||||
| RefSeq (mRNA) | NM_006494 | NM_010155 | |||||||||||
| RefSeq (protein) | NP_006485 | NP_034285 | |||||||||||
| Location (UCSC) | Chr 19: 42.75 – 42.76 Mb | Chr 7: 25.24 – 25.25 Mb | |||||||||||
| PubMed search | |||||||||||||
ETS domain-containing transcription factor ERF is a protein that in humans is encoded by the ERF gene.[1][2][3]
References
- ↑ Sgouras DN, Athanasiou MA, Beal GJ Jr, Fisher RJ, Blair DG, Mavrothalassitis GJ (Nov 1995). "ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation". EMBO J 14 (19): 4781–93. PMC 394576. PMID 7588608.
- ↑ de Castro CM, Rabe SM, Langdon SD, Fleenor DE, Slentz-Kesler K, Ahmed MN, Qumsiyeh MB, Kaufman RE (Sep 1997). "Genomic structure and chromosomal localization of the novel ETS factor, PE-2 (ERF)". Genomics 42 (2): 227–35. doi:10.1006/geno.1997.4730. PMID 9192842.
- ↑ "Entrez Gene: ERF Ets2 repressor factor".
Further reading
- Liu D, Pavlopoulos E, Modi W, et al. (1997). "ERF: genomic organization, chromosomal localization and promoter analysis of the human and mouse genes.". Oncogene 14 (12): 1445–51. doi:10.1038/sj.onc.1200965. PMID 9136988.
- Le Gallic L, Sgouras D, Beal G, Mavrothalassitis G (1999). "Transcriptional repressor ERF is a Ras/mitogen-activated protein kinase target that regulates cellular proliferation.". Mol. Cell. Biol. 19 (6): 4121–33. PMC 104371. PMID 10330152.
- Dintilhac A, Bernués J (2002). "HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences.". J. Biol. Chem. 277 (9): 7021–8. doi:10.1074/jbc.M108417200. PMID 11748221.
- Dubois T, Howell S, Zemlickova E, Aitken A (2002). "Identification of casein kinase Ialpha interacting protein partners.". FEBS Lett. 517 (1–3): 167–71. doi:10.1016/S0014-5793(02)02614-5. PMID 12062430.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Bain M, Mendelson M, Sinclair J (2003). "Ets-2 Repressor Factor (ERF) mediates repression of the human cytomegalovirus major immediate-early promoter in undifferentiated non-permissive cells". J. Gen. Virol. 84 (Pt 1): 41–9. doi:10.1099/vir.0.18633-0. PMID 12533699.
- Xiao X, Athanasiou M, Sidorov IA, et al. (2003). "Role of Ets/Id proteins for telomerase regulation in human cancer cells". Exp. Mol. Pathol. 75 (3): 238–47. doi:10.1016/S0014-4800(03)00092-3. PMID 14611815.
- Wolvetang EJ, Bradfield OM, Hatzistavrou T, et al. (2004). "Overexpression of the chromosome 21 transcription factor Ets2 induces neuronal apoptosis". Neurobiol. Dis. 14 (3): 349–56. doi:10.1016/S0969-9961(03)00107-4. PMID 14678752.
- Le Gallic L, Virgilio L, Cohen P, et al. (2004). "ERF nuclear shuttling, a continuous monitor of Erk activity that links it to cell cycle progression". Mol. Cell. Biol. 24 (3): 1206–18. doi:10.1128/MCB.24.3.1206-1218.2004. PMC 321421. PMID 14729966.
- Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19". Nature 428 (6982): 529–35. doi:10.1038/nature02399. PMID 15057824.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
- Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
- Hester KD, Verhelle D, Escoubet-Lozach L, et al. (2007). "Differential repression of c-myc and cdc2 gene expression by ERF and PE-1/METS". Cell Cycle 6 (13): 1594–604. doi:10.4161/cc.6.13.4336. PMID 17525531.
- Verykokakis M, Papadaki C, Vorgia E, et al. (2007). "The RAS-dependent ERF control of cell proliferation and differentiation is mediated by c-Myc repression". J. Biol. Chem. 282 (41): 30285–94. doi:10.1074/jbc.M704428200. PMID 17699159.
External links
- ERF protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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