EIF3G
From Wikipedia, the free encyclopedia
| Eukaryotic translation initiation factor 3, subunit G | |||||||||||||
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 PDB rendering based on 2cq0. | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | EIF3G; EIF3-P42; EIF3S4; eIF3-delta; eIF3-p44 | ||||||||||||
| External IDs | OMIM: 603913 MGI: 1858258 HomoloGene: 2784 GeneCards: EIF3G Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 8666 | 53356 | |||||||||||
| Ensembl | ENSG00000130811 | ENSMUSG00000070319 | |||||||||||
| UniProt | O75821 | Q9Z1D1 | |||||||||||
| RefSeq (mRNA) | NM_003755 | NM_016876 | |||||||||||
| RefSeq (protein) | NP_003746 | NP_058572 | |||||||||||
| Location (UCSC) | Chr 19: 10.23 – 10.23 Mb | Chr 9: 20.89 – 20.9 Mb | |||||||||||
| PubMed search | |||||||||||||
Eukaryotic translation initiation factor 3 subunit G is a protein that in humans is encoded by the EIF3G gene.[1][2]
Interactions
EIF3G has been shown to interact with Band 4.1,[3] EIF3C[1][4] and EIF3A.[1][5]
References
- ↑ 1.0 1.1 1.2 Block KL, Vornlocher HP, Hershey JW (December 1998). "Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3". J Biol Chem 273 (48): 31901–31908. doi:10.1074/jbc.273.48.31901. PMID 9822659.
- ↑ "Entrez Gene: EIF3S4 eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa".
- ↑ Hou, C L; Tang C j, Roffler S R, Tang T K (July 2000). "Protein 4.1R binding to eIF3-p44 suggests an interaction between the cytoskeletal network and the translation apparatus". Blood (UNITED STATES) 96 (2): 747–53. ISSN 0006-4971. PMID 10887144.
- ↑ Rual, Jean-François; Venkatesan Kavitha, Hao Tong, Hirozane-Kishikawa Tomoko, Dricot Amélie, Li Ning, Berriz Gabriel F, Gibbons Francis D, Dreze Matija, Ayivi-Guedehoussou Nono, Klitgord Niels, Simon Christophe, Boxem Mike, Milstein Stuart, Rosenberg Jennifer, Goldberg Debra S, Zhang Lan V, Wong Sharyl L, Franklin Giovanni, Li Siming, Albala Joanna S, Lim Janghoo, Fraughton Carlene, Llamosas Estelle, Cevik Sebiha, Bex Camille, Lamesch Philippe, Sikorski Robert S, Vandenhaute Jean, Zoghbi Huda Y, Smolyar Alex, Bosak Stephanie, Sequerra Reynaldo, Doucette-Stamm Lynn, Cusick Michael E, Hill David E, Roth Frederick P, Vidal Marc (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature (England) 437 (7062): 1173–1178. doi:10.1038/nature04209. PMID 16189514.
- ↑ Mayeur, Greg L; Fraser Christopher S, Peiretti Franck, Block Karen L, Hershey John W B (October 2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3". Eur. J. Biochem. (Germany) 270 (20): 4133–4139. doi:10.1046/j.1432-1033.2003.03807.x. ISSN 0014-2956. PMID 14519125.
Further reading
- Hillier LD, Lennon G, Becker M et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res. 6 (9): 807–828. doi:10.1101/gr.6.9.807. PMID 8889549.
- Asano K, Kinzy TG, Merrick WC, Hershey JW (1997). "Conservation and diversity of eukaryotic translation initiation factor eIF3". J. Biol. Chem. 272 (2): 1101–1109. doi:10.1074/jbc.272.2.1101. PMID 8995409.
- Méthot N, Rom E, Olsen H, Sonenberg N (1997). "The human homologue of the yeast Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170". J. Biol. Chem. 272 (2): 1110–1116. doi:10.1074/jbc.272.2.1110. PMID 8995410.
- Bandyopadhyay A, Maitra U (1999). "Cloning and characterization of the p42 subunit of mammalian translation initiation factor 3 (eIF3): demonstration that eIF3 interacts with eIF5 in mammalian cells". Nucleic Acids Res. 27 (5): 1331–1337. doi:10.1093/nar/27.5.1331. PMC 148320. PMID 9973622.
- Hou CL, Tang C, Roffler SR, Tang TK (2000). "Protein 4.1R binding to eIF3-p44 suggests an interaction between the cytoskeletal network and the translation apparatus". Blood 96 (2): 747–53. PMID 10887144.
- Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Mayeur GL, Fraser CS, Peiretti F et al. (2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3". Eur. J. Biochem. 270 (20): 4133–4139. doi:10.1046/j.1432-1033.2003.03807.x. PMID 14519125.
- Fraser CS, Lee JY, Mayeur GL et al. (2004). "The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro". J. Biol. Chem. 279 (10): 8946–8956. doi:10.1074/jbc.M312745200. PMID 14688252.
- Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–1323. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
- Beausoleil SA, Jedrychowski M, Schwartz D et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–12135. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
- Gerhard DS, Wagner L, Feingold EA et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Rual JF, Venkatesan K, Hao T et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–1178. doi:10.1038/nature04209. PMID 16189514.
- Ogawa F, Kasai M, Akiyama T (2006). "A functional link between Disrupted-In-Schizophrenia 1 and the eukaryotic translation initiation factor 3". Biochem. Biophys. Res. Commun. 338 (2): 771–776. doi:10.1016/j.bbrc.2005.10.013. PMID 16243297.
- Kim JT, Kim KD, Song EY et al. (2007). "Apoptosis-inducing factor (AIF) inhibits protein synthesis by interacting with the eukaryotic translation initiation factor 3 subunit p44 (eIF3g)". FEBS Lett. 580 (27): 6375–6383. doi:10.1016/j.febslet.2006.10.049. PMID 17094969.
- Ewing RM, Chu P, Elisma F et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
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