Dihydralazine

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Dihydralazine


Systematic (IUPAC) name
4-hydrazinyl-1-hydrazinylidene-1,2-dihydrophthalazine
Clinical data
AHFS/Drugs.com	International Drug Names
Legal status	?
Identifiers
CAS number	484-23-1^N
ATC code	C02DB01
PubChem	CID 10230
ChemSpider	9813^Y
UNII	PCU411F5L6^Y
KEGG	D07170^Y
ChEMBL	CHEMBL35505^Y
Chemical data
Formula	C₈H₁₀N₆
Mol. mass	190.205 g/mol
SMILES n2nc(c1ccccc1c2NN)NN
InChI InChI=1S/C8H10N6/c9-11-7-5-3-1-2-4-6(5)8(12-10)14-13-7/h1-4H,9-10H2,(H,11,13)(H,12,14)^Y Key:VQKLRVZQQYVIJW-UHFFFAOYSA-N^Y
N (what is this?) (verify)

Dihydralazine is a drug with antihypertensive properties.^[1] It belongs to the hydrazinophthalazine chemical class.^[2] It has very similar effects to hydralazine.^[2]

References

↑ Stern, H. C.; Matthews, J. H.; Belz, G. G. (1984). "Influence of dihydralazine induced afterload reduction on systolic time intervals and echocardiography in healthy subjects". British heart journal 52 (4): 435–439. PMC 481656. PMID 6477782.
↑ 2.0 2.1 Bourreli, B.; Pinaud, M.; Passuti, N.; Gunst, J. P.; Drouet, J. C.; Remi, J. P. (1988). "Additive effects of dihydralazine during enflurane or isoflurane hypotensive anaesthesia for spinal fusion". Canadian Journal of Anaesthesia 35 (3): 242–248. doi:10.1007/BF03010617. PMID 3383316.

Nonsympatholytic vasodilatory antihypertensives (C02)

Nitrovasodilator

NO (arterioles and venules)	Nitroprusside #

N (arteriolar)	Hydrazines Hydralazine # Dihydralazine Endralazine Cadralazine Pildralazine

(arteriolar) Potassium channel opener

(arteriolar) Calcium channel blocker

see list

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

M: VAS

anat (a:h/u/t/a/l,v:h/u/t/a/l)/phys/devp/cell/prot

noco/syva/cong/lyvd/tumr, sysi/epon, injr

proc, drug (C2s+n/3/4/5/7/8/9)

Hydrazines

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