Dexamethasone isonicotinate

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Dexamethasone isonicotinate
IUPAC name

[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl]pyridine-4-carboxylate

Other names

Auxiloson/ Dexamethasone 21-isonicotinate/ Auxilson/ Auxilsone/ Voren/ DEXAMETHASONE ISONICOTINATE/ EINECS 218-866-5/ HE 111/ 2265-64-7/ Pyridine-4-carboxylic acid-(dexamethasone-21') ester/ Pyridin-4-carbonsaeure-(dexamethason-21')-ester [German]/ Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-((4-pyridinylcarbonyl)oxy)-, (11beta,16alpha)/ Pregna-1,4-diene-3,20-dione, 9-fluoro-11-beta,17,21-trihydroxy-16-alpha-methyl-, 21-isonicotinate/ Auxison/ Voren [veterinary] (TN)/ UNII-8LGC0BOA71/ AC1L28M0/ C28H32FNO6/ HE-111/ LS-118477/ D07797/ Pyridin-4-carbonsaeure-(dexamethason-21')-ester/ Pregna-1,4-diene-3,20-dione, 9-fluoro-11-beta,17,21-trihydroxy-16-alpha-methyl-,21-isonicotinate

Identifiers
CAS number 2265-64-7
PubChem 16752
ChemSpider 15881
Jmol-3D images {{#if:O=C(OCC(=O)[C@@]3(O)[C@H](C)C[C@H]2[C@@H]4CCC\1=C\C(=O)\C=C/[C@]/1(C)[C@@]4(F)[C@@H](O)C[C@@]23C)c5ccncc5|Image 1
Properties
Molecular formula C28H32FNO6
Molar mass 497.56 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references
See also: dexamethasone

Dexamethasone isonicotinate is an anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, locally, and parenterally. It may cause salt and water retention.

See also

References

    Corticosteroids – glucocorticoids and mineralocorticoids (H02)
    (also A07EA, C05AA, D07, D10AA, R01AD, R03BA, S01BA, S02B, and S03B)
    Mineralocorticoids
    (3-one, 4-ene,
    no FG at 16)
    Glucocorticoids
    (3-one, 4-ene,
    11-FG,
    17-hydroxy)
    Pregnenedione
    (+20-one)
    Pregnadiene (+1-ene)
    Pregnadienediol
    (+21-hydroxy)
    Pregnadienetriol
    (+11-hydroxy)
    Pregnatriene
    (+2-ene)
    Other/ungrouped
    Aldosterone antagonists
    Synthesis modifiers

    M: END

    anat/phys/devp/horm

    noco (d)/cong/tumr, sysi/epon

    proc, drug (A10/H1/H2/H3/H5)


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