Desmoplastic melanoma

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Desmoplastic melanoma
Infiltration of perineurium

Desmoplastic melanoma (also known as a "Neurotropic melanoma,"[1] or "Spindled melanoma"[1]) is a rare cutaneous condition characterized by a deeply infiltrating type of melanoma[2]:696 with an abundance of fibrous matrix.[3] It usually occurs in the head and neck region of older people with sun-damaged skin.[3] Diagnosis can be difficult as it has a similar appearance to sclerosing melanocytic nevi as well as some nonmelanocytic skin lesions such as scars, fibromas, or cysts.[3]

Desmoplastic melanomas tend to recur locally, with distant metastasis being less common.[3]

See also

References

  1. ↑ 1.0 1.1 Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0. 
  2. ↑ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0. 
  3. ↑ 3.0 3.1 3.2 3.3 Busam, Klaus J. (2011). "Desmoplastic Melanoma". Clinics in Laboratory Medicine 31 (2). 
Tumors: Skin neoplasm, Nevi and melanomas (C43/D22, 172/216, ICD-O 8720-8799)
Melanoma
Nevus/
melanocytic nevus
  • Blue nevus
    • of Jadassohn–Tièche
    • Cellular
    • Epithelioid
    • Deep penetrating
    • Amelanotic
    • Malignant

M: INT, SF, LCT

anat/phys/devp

noco (i/b/d/q/u/r/p/m/k/v/f)/cong/tumr (n/e/d), sysi/epon

proc, drug (D2/3/4/5/8/11)


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