Delapril

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Delapril

Systematic (IUPAC) name
2-[(2S)-N-(2,3-dihydro-1H-inden-2-yl)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanamido]acetic acid
Clinical data
AHFS/Drugs.com	International Drug Names
Legal status	?
Identifiers
CAS number	83435-66-9^Y
ATC code	C09AA12
PubChem	CID 5362116
ChemSpider	4514931
UNII	W77UAL9THI^Y
KEGG	D07781^Y
Chemical data
Formula	C₂₆H₃₂N₂O₅
Mol. mass	452.542 g/mol
SMILES O=C(OCC)[C@@H](N[C@H](C(=O)N(CC(=O)O)C2Cc1ccccc1C2)C)CCc3ccccc3
InChI InChI=1S/C26H32N2O5/c1-3-33-26(32)23(14-13-19-9-5-4-6-10-19)27-18(2)25(31)28(17-24(29)30)22-15-20-11-7-8-12-21(20)16-22/h4-12,18,22-23,27H,3,13-17H2,1-2H3,(H,29,30)/t18-,23-/m0/s1 Key:WOUOLAUOZXOLJQ-MBSDFSHPSA-N
Y (what is this?) (verify)

Delapril (INN, also known as alindapril) is an ACE inhibitor used as an antihypertensive drug^[1] in a number of European and Asian countries.^[2]

References

↑ Otero, M. L. (2007). "Manidipine-delapril combination in the management of hypertension". Vascular health and risk management 3 (3): 255–263. PMC 2293964. PMID 17703633.
↑ Drugs.com: Delapril

Antihypertensives: agents acting on the renin–angiotensin system (C09)

ACE inhibitors
("-pril")

Sulfhydryl-containing: Captopril
Zofenopril

Dicarboxylate-containing: Enalapril^#
Ramipril
Quinapril (+HCT)
Perindopril
Lisinopril (+HCT)
Benazepril

Phosphonate-containing: Fosinopril (+HCT)

AIIRAs/
("-sartan")

Renin inhibitors/
("-kiren")

Aliskiren (+amlodipine, +amlodipine and HCT)
Remikiren^§

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

M: VAS

anat (a:h/u/t/a/l,v:h/u/t/a/l)/phys/devp/cell/prot

noco/syva/cong/lyvd/tumr, sysi/epon, injr

proc, drug (C2s+n/3/4/5/7/8/9)

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