Cutaneous small-vessel vasculitis

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Cutaneous small-vessel vasculitis (also known as "Cutaneous leukocytoclastic angiitis,"[1] "Cutaneous leukocytoclastic vasculitis,"[1] "Cutaneous necrotizing venulitis,"[1] and "Hypersensitivity angiitis"[1]) is inflammation of small blood vessels (usually post-capillary venules in the dermis), characterized by palpable purpura.[2]:831[3] It is the most common vasculitis seen in clinical practice. Leukocytoclasis refers to the damage caused by nuclear debris from infiltrating neutrophils in and around the vessels.[4]

Subtypes of small-vessel vasculitis include:[2]:833-6

Leukocytoclastic vasculitis

  • LV1,2010.JPG
  • LV22010.JPG
  • Leukocytoclastic vasculitis caused by reaction to minocycline.jpg
  • LV4.JPG

See also

References

  1. ↑ 1.0 1.1 1.2 1.3 Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0. 
  2. ↑ 2.0 2.1 James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0. 
  3. ↑ Lotti T, Ghersetich I, Comacchi C, Jorizzo JL (November 1998). "Cutaneous small-vessel vasculitis". J. Am. Acad. Dermatol. 39 (5 Pt 1): 667–87; quiz 688–90. doi:10.1016/S0190-9622(98)70039-8. PMID 9810883. 
  4. ↑ Harrison's Principles of Internal Medicine. 18th edition. Page 2798.
Cutaneous vasculitis and other vascular-related cutaneous conditions (L95, 709.1)
Cutaneous
vasculitis
Microvascular occlusion
Purpura
Systemic vasculitis
  • see Template:Systemic vasculitis
Vascular malformations
Ulcer
Lymphedema
  • see Template:Lymphatic disease
Ungrouped
vascular-related
cutaneous
conditions

M: INT, SF, LCT

anat/phys/devp

noco (i/b/d/q/u/r/p/m/k/v/f)/cong/tumr (n/e/d), sysi/epon

proc, drug (D2/3/4/5/8/11)

Large vessel
Medium vessel
Small vessel
Pauci-immune
Type III hypersensitivity
Ungrouped
Other

M: VAS

anat (a:h/u/t/a/l,v:h/u/t/a/l)/phys/devp/cell/prot

noco/syva/cong/lyvd/tumr, sysi/epon, injr

proc, drug (C2s+n/3/4/5/7/8/9)

Type I/allergy/atopy
(IgE)
Foreign
Autoimmune
  • none
Type II/ADCC
Foreign
Autoimmune
Cytotoxic
"Type 5"/receptor
Type III
(Immune complex)
Foreign
Autoimmune
Type IV/cell-mediated
(T cells)
Foreign
Autoimmune
GVHD
Unknown/
multiple
Foreign
Autoimmune

M: LMC

cell/phys/auag/auab/comp, igrc

imdf/ipig/hyps/tumr

proc, drug (L3/4)

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