Croconazole

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Croconazole

Systematic (IUPAC) name
1-(1-{2-[(3-chlorophenyl)methoxy]phenyl}ethenyl)-1H-imidazole
Clinical data
AHFS/Drugs.com	International Drug Names
Legal status	℞ Prescription only
Routes	Topical
Identifiers
CAS number	77175-51-0
ATC code	None
PubChem	CID 2880
ChemSpider	2777
UNII	446254H55G^Y
KEGG	D07752
ChEMBL	CHEMBL27289
Chemical data
Formula	C₁₈H₁₅Cl N₂O
Mol. mass	310.77 g/mol
SMILES Clc1cccc(c1)COc3c(\C(=C)n2ccnc2)cccc3

Croconazole (INN) is an imidazole antifungal.

Wall/
membrane

Ergosterol
inhibitors

Imidazoles	topical: Bifonazole Butoconazole Clomidazole Clotrimazole^#, Croconazole Econazole Fenticonazole Ketoconazole Isoconazole Miconazole^#, Neticonazole Omoconazole Oxiconazole Sertaconazole Sulconazole Tioconazole

Triazoles	topical: (Fluconazole^#, Fosfluconazole Terconazole) systemic: (Fluconazole Hexaconazole Isavuconazole^†, Itraconazole Posaconazole Voriconazole) unknown: (Albaconazole)

Thiazoles	topical: (Abafungin)

β-glucan synthase
inhibitors

Intracellular

Pyrimidine analogues/ Thymidylate synthase inhibitors	Flucytosine^#

Mitotic inhibitors	Griseofulvin^#

Others

fung, clas

fung

drug (fung)

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