Combretastatin B-1

From Wikipedia, the free encyclopedia

Combretastatin B-1

IUPAC name 3-methoxy-6-[2-(3,4,5-trimethoxyphenyl)ethyl]benzene-1,2-diol
Other names Combretastatin B1
Identifiers
CAS number	109971-64-4
PubChem	135716
ChemSpider	119539
Jmol-3D images	Image 1
SMILES O(c1cc(cc(OC)c1OC)CCc2ccc(OC)c(O)c2O)C
InChI InChI=1S/C18H22O6/c1-21-13-8-7-12(16(19)17(13)20)6-5-11-9-14(22-2)18(24-4)15(10-11)23-3/h7-10,19-20H,5-6H2,1-4H3 Key: ZSNYQENLWQYSRK-UHFFFAOYSA-N InChI=1/C18H22O6/c1-21-13-8-7-12(16(19)17(13)20)6-5-11-9-14(22-2)18(24-4)15(10-11)23-3/h7-10,19-20H,5-6H2,1-4H3 Key: ZSNYQENLWQYSRK-UHFFFAOYAW
Properties
Molecular formula	C₁₈H_22O₆
Molar mass	334.36 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Combretastatin B-1 is a combretastatin and a dihydrostilbenoid. It can be found in Combretum caffrum, the Eastern Cape South African bushwillow tree^[1] or in Combretum kraussii, the forest bushwillow.^[2]

References

↑ Pettit, G. R.; Singh, S. B.; Niven, M. L.; Hamel, E.; Schmidt, J. M. (1987). "Isolation, Structure, and Synthesis of Combretastatins A-1 and B-1, Potent New Inhibitors of Microtubule Assembly, Derived from Combretum caffrum". Journal of Natural Products 50 (1): 119–131. doi:10.1021/np50049a016. PMID 3598594.
↑ Uteroactive constituents from Combretum kraussii. Bridget K Brookes, Olga V Doudoukina, Lynn C Katsoulis and Joy H D Veale, South African Journal of Chemistry, Dec 99, Vol. 52, Issue 4, page 127 (abstract)

v t e Dihydrostilbenoids and their glycosides

Dihydrostilbenoids	Combretastatin and combretastatin B-1 Dihydro-resveratrol Isonotholaenic acid Lunularic acid Lunularin Notholaenic acid

Oligomeric forms	Bis(bibenzyls): 13,13'-O-Isoproylidenericcardin D Marchantin B and E Neomarchantin A Plagiochin E Riccardin H Macrocyclic bis(benzyls): Marchantin A and C Riccardin B and C Cyclic bibenzyl-dihydrophenanthrene derivative: Cavicularin

This article is issued from Wikipedia. The text is available under the Creative Commons Attribution/Share Alike; additional terms may apply for the media files.