Cloprednol

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Cloprednol
Systematic (IUPAC) name
(9S,10R,11S,13S,14S,17R)-6-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-9,11,12,14,15,16-hexahydro-8H-cyclopenta[a]phenanthren-3-one
Clinical data
AHFS/Drugs.com International Drug Names
Legal status ?
Identifiers
CAS number 5251-34-3
ATC code H02AB14
PubChem CID 10023463
ChemSpider 4447592
UNII SYP56O3GJG YesY
KEGG D03561
Chemical data
Formula C21H25ClO5 
Mol. mass 392.873

Cloprednol is a synthetic glucocorticoid.[1] It has been investigated for use in asthma.[2]

References

  1. ↑ Ortega E, Rodriguez C, Strand LJ, Bessler S, Segre E (1976). "Metabolic effects of cloprednol-a new systemic corticosteroid". J Clin Pharmacol 16 (2-3): 122–8. PMID 1254734. 
  2. ↑ Ellis EF, Morris HG, Kiechel F, Pollock JD, Strand LJ (October 1979). "Short-term efficacy and side effects of cloprednol in children with asthma". J Clin Pharmacol 19 (10): 675–83. PMID 512064. 
Corticosteroids – glucocorticoids and mineralocorticoids (H02)
(also A07EA, C05AA, D07, D10AA, R01AD, R03BA, S01BA, S02B, and S03B)
Mineralocorticoids
(3-one, 4-ene,
no FG at 16)
Glucocorticoids
(3-one, 4-ene,
11-FG,
17-hydroxy)
Pregnenedione
(+20-one)
Pregnadiene (+1-ene)
Pregnadienediol
(+21-hydroxy)
Pregnadienetriol
(+11-hydroxy)
Pregnatriene
(+2-ene)
Other/ungrouped
Aldosterone antagonists
Synthesis modifiers

M: END

anat/phys/devp/horm

noco (d)/cong/tumr, sysi/epon

proc, drug (A10/H1/H2/H3/H5)


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