CatSper3

From Wikipedia, the free encyclopedia
cation channel, sperm associated 3
Identifiers
SymbolCATSPER3
External IDsOMIM: 609120 MGI: 1924106 HomoloGene: 12658 IUPHAR: CatSper3 GeneCards: CATSPER3 Gene
Orthologs
SpeciesHumanMouse
Entrez34773276856
EnsemblENSG00000152705ENSMUSG00000021499
UniProtQ86XQ3Q80W99
RefSeq (mRNA)NM_178019NM_029772
RefSeq (protein)NP_821138NP_084048
Location (UCSC)Chr 5:
134.33 – 134.38 Mb
Chr 13:
55.89 – 55.91 Mb
PubMed search

CatSper3, is a protein which in humans is encoded by the CATSPER3 gene.[1][2][3][4] CatSper3 is a member of the cation channels of sperm family of proteins. The four proteins in this family together form a Ca2+-permeant ion channel specific essential for the correct function of sperm cells.[5]

References

  1. Arias JM, n J, Murbartiá Perez-Reyes E (March 2003). "Cloning of a novel one-repeat calcium channel-like gene". Biochem. Biophys. Res. Commun. 303 (1): 31–6. doi:10.1016/S0006-291X(03)00276-6. PMID 12646162. 
  2. Lobley A, Pierron V, Reynolds L, Allen L, Michalovich D (August 2003). "Identification of human and mouse CatSper3 and CatSper4 genes: Characterisation of a common interaction domain and evidence for expression in testis". Reprod. Biol. Endocrinol. 1: 53. doi:10.1186/1477-7827-1-53. PMC 184451. PMID 12932298. 
  3. Qi H, Moran MM, Navarro B, Chong JA, Krapivinsky G, Krapivinsky L, Kirichok Y, Ramsey IS, Quill TA (January 2007). "All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility". Proc. Natl. Acad. Sci. U.S.A. 104 (4): 1219–23. doi:10.1073/pnas.0610286104. PMC 1770895. PMID 17227845. 
  4. Clapham DE, Garbers DL (December 2005). "International Union of Pharmacology. L. Nomenclature and structure-function relationships of CatSper and two-pore channels". Pharmacol. Rev. 57 (4): 451–4. doi:10.1124/pr.57.4.7. PMID 16382101. 


This article is issued from Wikipedia. The text is available under the Creative Commons Attribution/Share Alike; additional terms may apply for the media files.