CapZ
From Wikipedia, the free encyclopedia
This image shows the structures of Cap32/34 superposed onto CapZ (in green) over the CĪ± positions of the entire CP molecules.[1]
In molecular biology CapZ is a protein that caps the barbed (plus) end of actin filaments in muscle cells. It is located in the Z band of the muscle sarcomere.
A modest reduction in cardiac CapZ protein protects hearts against acute ischemia-reperfusion injury.[2]
References
- ā Eckert, C.; Goretzki, A.; Faberova, M.; Kollmar, M. (2012). "Conservation and divergence between cytoplasmic and muscle-specific actin capping proteins: Insights from the crystal structure of cytoplasmic Cap32/34 from Dictyostelium discoideum". BMC Structural Biology 12: 12. doi:10.1186/1472-6807-12-12. PMC 3472329. PMID 22657106.
- ā Yang, Feng Hua; Pyle, WG (2 Dec 2011). "Reduced cardiac CapZ protein protects hearts against acute ischemia-reperfusion injury and enhances preconditioning". Journal of Molecular and Cellular Cardiology epub (3): 761ā72. doi:10.1016/j.yjmcc.2011.11.013. PMID 22155006.
Genes
External links
- CapZ Actin Capping Protein at the US National Library of Medicine Medical Subject Headings (MeSH)
- CyMoBase - Database of cytoskeletal and motor protein sequences
This article is issued from Wikipedia. The text is available under the Creative Commons Attribution/Share Alike; additional terms may apply for the media files.