Camostat

From Wikipedia, the free encyclopedia

Camostat

Systematic (IUPAC) name
N,N-dimethylcarbamoylmethyl 4-(4-guanidinobenzoyloxy)phenylacetate
Clinical data
AHFS/Drugs.com	International Drug Names
Legal status	℞ Prescription only
Routes	Oral
Identifiers
CAS number	59721-29-8^Y (mesylate)
ATC code	B02AB04
PubChem	CID 2536
ChemSpider	2440^Y
UNII	0FD207WKDU^Y
ChEMBL	CHEMBL590799^Y
Chemical data
Formula	C₂₀H₂₂N₄O₅
Mol. mass	398.41 g/mol
SMILES CN(C)C(=O)COC(=O)CC1=CC=C(C=C1)OC(=O)C2=CC=C(C=C2)N=C(N)N
InChI InChI=1S/C20H22N4O5/c1-24(2)17(25)12-28-18(26)11-13-3-9-16(10-4-13)29-19(27)14-5-7-15(8-6-14)23-20(21)22/h3-10H,11-12H2,1-2H3,(H4,21,22,23)^Y Key:XASIMHXSUQUHLV-UHFFFAOYSA-N^Y
Y (what is this?) (verify)

Camostat (INN) is a serine protease inhibitor.

References

Kunze H, Bohn E (May 1983). "Effects of the serine protease inhibitors FOY and FOY 305 on phospholipase A1 (EC 3.1.1.32) activity in rat - liver lysosomes". Pharmacol Res Commun 15 (5): 451–9. doi:10.1016/S0031-6989(83)80065-4. PMID 6412250.
Göke B, Stöckmann F, Müller R, Lankisch PG, Creutzfeldt W (1984). "Effect of a specific serine protease inhibitor on the rat pancreas: systemic administration of camostate and exocrine pancreatic secretion". Digestion 30 (3): 171–8. doi:10.1159/000199102. PMID 6209186.

This article is issued from Wikipedia. The text is available under the Creative Commons Attribution/Share Alike; additional terms may apply for the media files.