CYP26C1

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Cytochrome P450, family 26, subfamily C, polypeptide 1
Identifiers
SymbolsCYP26C1; FFDD4
External IDsOMIM: 608428 MGI: 2679699 HomoloGene: 28089 GeneCards: CYP26C1 Gene
EC number1.14.-.-
Orthologs
SpeciesHumanMouse
Entrez340665546726
EnsemblENSG00000187553ENSMUSG00000062432
UniProtQ6V0L0B2RXA7
RefSeq (mRNA)NM_183374NM_001105201
RefSeq (protein)NP_899230NP_001098671
Location (UCSC)Chr 10:
94.82 – 94.83 Mb
Chr 19:
37.69 – 37.69 Mb
PubMed search

CYP26C1 (cytochrome P450, family 26, subfamily c, polypeptide 1) is a protein which in humans is encoded by the CYP26C1 gene.[1]

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is involved in the catabolism of all-trans- and 9-cis-retinoic acid, and thus contributes to the regulation of retinoic acid levels in cells and tissues.[2]

References

  1. Taimi M, Helvig C, Wisniewski J, et al. (January 2004). "A novel human cytochrome P450, CYP26C1, involved in metabolism of 9-cis and all-trans isomers of retinoic acid". J. Biol. Chem. 279 (1): 77–85. doi:10.1074/jbc.M308337200. PMID 14532297. 
  2. "Entrez Gene: CYP26C1". 

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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