CNOT8

From Wikipedia, the free encyclopedia
CCR4-NOT transcription complex, subunit 8
Identifiers
SymbolsCNOT8; CAF1; CALIF; POP2; hCAF1
External IDsOMIM: 603731 MGI: 1916375 HomoloGene: 48304 GeneCards: CNOT8 Gene
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez933769125
EnsemblENSG00000155508ENSMUSG00000020515
UniProtQ9UFF9Q9D8X5
RefSeq (mRNA)NM_004779NM_026949
RefSeq (protein)NP_004770NP_081225
Location (UCSC)Chr 5:
154.24 – 154.26 Mb
Chr 11:
58.1 – 58.12 Mb
PubMed search

CCR4-NOT transcription complex subunit 8 is a protein that in humans is encoded by the CNOT8 gene.[1][2][3]

Interactions

CNOT8 has been shown to interact with BTG2,[4] BTG1,[4][5] CNOT1[2][6] and CNOT3.[2]

References

  1. Fidler C, Wainscoat JS, Boultwood J (May 1999). "The human POP2 gene: identification, sequencing, and mapping to the critical region of the 5q- syndrome". Genomics 56 (1): 134–6. doi:10.1006/geno.1998.5687. PMID 10036195. 
  2. 2.0 2.1 2.2 Albert TK, Lemaire M, van Berkum NL, Gentz R, Collart MA, Timmers HT (March 2000). "Isolation and characterization of human orthologs of yeast CCR4–NOT complex subunits". Nucleic Acids Res 28 (3): 809–17. doi:10.1093/nar/28.3.809. PMC 102560. PMID 10637334. 
  3. "Entrez Gene: CNOT8 CCR4-NOT transcription complex, subunit 8". 
  4. 4.0 4.1 Prévôt, D; Morel A P, Voeltzel T, Rostan M C, Rimokh R, Magaud J P, Corbo L (March 2001). "Relationships of the antiproliferative proteins BTG1 and BTG2 with CAF1, the human homolog of a component of the yeast CCR4 transcriptional complex: involvement in estrogen receptor alpha signaling pathway". J. Biol. Chem. (United States) 276 (13): 9640–8. doi:10.1074/jbc.M008201200. ISSN 0021-9258. PMID 11136725. 
  5. Rual, Jean-François; Venkatesan Kavitha, Hao Tong, Hirozane-Kishikawa Tomoko, Dricot Amélie, Li Ning, Berriz Gabriel F, Gibbons Francis D, Dreze Matija, Ayivi-Guedehoussou Nono, Klitgord Niels, Simon Christophe, Boxem Mike, Milstein Stuart, Rosenberg Jennifer, Goldberg Debra S, Zhang Lan V, Wong Sharyl L, Franklin Giovanni, Li Siming, Albala Joanna S, Lim Janghoo, Fraughton Carlene, Llamosas Estelle, Cevik Sebiha, Bex Camille, Lamesch Philippe, Sikorski Robert S, Vandenhaute Jean, Zoghbi Huda Y, Smolyar Alex, Bosak Stephanie, Sequerra Reynaldo, Doucette-Stamm Lynn, Cusick Michael E, Hill David E, Roth Frederick P, Vidal Marc (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature (England) 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  6. Ewing, Rob M; Chu Peter, Elisma Fred, Li Hongyan, Taylor Paul, Climie Shane, McBroom-Cerajewski Linda, Robinson Mark D, O'Connor Liam, Li Michael, Taylor Rod, Dharsee Moyez, Ho Yuen, Heilbut Adrian, Moore Lynda, Zhang Shudong, Ornatsky Olga, Bukhman Yury V, Ethier Martin, Sheng Yinglun, Vasilescu Julian, Abu-Farha Mohamed, Lambert Jean-Philippe, Duewel Henry S, Stewart Ian I, Kuehl Bonnie, Hogue Kelly, Colwill Karen, Gladwish Katharine, Muskat Brenda, Kinach Robert, Adams Sally-Lin, Moran Michael F, Morin Gregg B, Topaloglou Thodoros, Figeys Daniel (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. (England) 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. 

Further reading


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