CLDN6
From Wikipedia, the free encyclopedia
| Claudin 6 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbol | CLDN6 | ||||||||||||
| External IDs | MGI: 1859284 HomoloGene: 10300 GeneCards: CLDN6 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 9074 | 54419 | |||||||||||
| Ensembl | ENSG00000184697 | ENSMUSG00000023906 | |||||||||||
| UniProt | P56747 | Q9Z262 | |||||||||||
| RefSeq (mRNA) | NM_021195 | NM_018777 | |||||||||||
| RefSeq (protein) | NP_067018 | NP_061247 | |||||||||||
| Location (UCSC) | Chr 16: 3.06 – 3.07 Mb | Chr 17: 23.68 – 23.68 Mb | |||||||||||
| PubMed search | |||||||||||||
Claudin-6 is a protein that in humans is encoded by the CLDN6 gene.[1][2][3] It belongs to the group of claudins.
References
- ↑ Morita K, Furuse M, Fujimoto K, Tsukita S (Mar 1999). "Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands". Proc Natl Acad Sci U S A 96 (2): 511–6. doi:10.1073/pnas.96.2.511. PMC 15167. PMID 9892664.
- ↑ Meertens L, Bertaux C, Cukierman L, Cormier E, Lavillette D, Cosset FL, Dragic T (Mar 2008). "The Tight Junction Proteins Claudin-1, -6, and -9 Are Entry Cofactors for Hepatitis C Virus". J Virol 82 (7): 3555–60. doi:10.1128/JVI.01977-07. PMC 2268462. PMID 18234789.
- ↑ "Entrez Gene: CLDN6 claudin 6".
Further reading
- Kniesel U, Wolburg H (2000). "Tight junctions of the blood–brain barrier". Cell. Mol. Neurobiol. 20 (1): 57–76. doi:10.1023/A:1006995910836. PMID 10690502.
- Heiskala M, Peterson PA, Yang Y (2001). "The roles of claudin superfamily proteins in paracellular transport". Traffic 2 (2): 93–8. doi:10.1034/j.1600-0854.2001.020203.x. PMID 11247307.
- Tsukita S, Furuse M, Itoh M (2001). "Multifunctional strands in tight junctions". Nat. Rev. Mol. Cell Biol. 2 (4): 285–93. doi:10.1038/35067088. PMID 11283726.
- Tsukita S, Furuse M (2003). "Claudin-based barrier in simple and stratified cellular sheets". Curr. Opin. Cell Biol. 14 (5): 531–6. doi:10.1016/S0955-0674(02)00362-9. PMID 12231346.
- González-Mariscal L, Betanzos A, Nava P, Jaramillo BE (2003). "Tight junction proteins". Prog. Biophys. Mol. Biol. 81 (1): 1–44. doi:10.1016/S0079-6107(02)00037-8. PMID 12475568.
- Morita K, Sasaki H, Furuse M, Tsukita S (1999). "Endothelial Claudin: Claudin-5/Tmvcf Constitutes Tight Junction Strands in Endothelial Cells". J. Cell Biol. 147 (1): 185–94. doi:10.1083/jcb.147.1.185. PMC 2164984. PMID 10508865.
- Itoh M, Furuse M, Morita K, et al. (2000). "Direct Binding of Three Tight Junction-Associated Maguks, Zo-1, Zo-2, and Zo-3, with the Cooh Termini of Claudins". J. Cell Biol. 147 (6): 1351–63. doi:10.1083/jcb.147.6.1351. PMC 2168087. PMID 10601346.
- Turksen K, Troy TC (2001). "Claudin-6: a novel tight junction molecule is developmentally regulated in mouse embryonic epithelium". Dev. Dyn. 222 (2): 292–300. doi:10.1002/dvdy.1174. PMID 11668606.
- Kiuchi-Saishin Y, Gotoh S, Furuse M, et al. (2002). "Differential expression patterns of claudins, tight junction membrane proteins, in mouse nephron segments". J. Am. Soc. Nephrol. 13 (4): 875–86. PMID 11912246.
- Turksen K, Troy TC (2002). "Permeability barrier dysfunction in transgenic mice overexpressing claudin 6". Development 129 (7): 1775–84. PMID 11923212.
- Morita K, Furuse M, Yoshida Y, et al. (2002). "Molecular architecture of tight junctions of periderm differs from that of the maculae occludentes of epidermis". J. Invest. Dermatol. 118 (6): 1073–9. doi:10.1046/j.1523-1747.2002.01774.x. PMID 12060405.
- Reyes JL, Lamas M, Martin D, et al. (2003). "The renal segmental distribution of claudins changes with development". Kidney Int. 62 (2): 476–87. doi:10.1046/j.1523-1755.2002.00479.x. PMID 12110008.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Katoh M, Katoh M (2004). "CLDN23 gene, frequently down-regulated in intestinal-type gastric cancer, is a novel member of CLAUDIN gene family". Int. J. Mol. Med. 11 (6): 683–9. PMID 12736707.
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