CLDN20

From Wikipedia, the free encyclopedia

Claudin 20

Identifiers

External IDs

MGI: 3646757 HomoloGene: 47972 GeneCards: CLDN20 Gene

Gene Ontology
Molecular function	• structural molecule activity • identical protein binding
Cellular component	• plasma membrane • tight junction • integral to membrane
Biological process	• calcium-independent cell-cell adhesion • cell junction assembly • cell-cell junction organization • tight junction assembly
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

ENSG00000171217

ENSMUSG00000091530

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 6:
155.59 – 155.6 Mb

Chr 17:
3.53 – 3.53 Mb

PubMed search

Claudin-20 is a protein that in humans is encoded by the CLDN20 gene.^[1]^[2] It belongs to the group of claudins.

References

↑ Hewitt KJ, Agarwal R, Morin PJ (Aug 2006). "The claudin gene family: expression in normal and neoplastic tissues". BMC Cancer 6: 186. doi:10.1186/1471-2407-6-186. PMC 1538620. PMID 16836752.
↑ "Entrez Gene: CLDN20 claudin 20".

Further reading

Kniesel U, Wolburg H (2000). "Tight junctions of the blood–brain barrier". Cell. Mol. Neurobiol. 20 (1): 57–76. doi:10.1023/A:1006995910836. PMID 10690502.
Heiskala M, Peterson PA, Yang Y (2001). "The roles of claudin superfamily proteins in paracellular transport". Traffic 2 (2): 93–8. doi:10.1034/j.1600-0854.2001.020203.x. PMID 11247307.
Tsukita S, Furuse M, Itoh M (2001). "Multifunctional strands in tight junctions". Nat. Rev. Mol. Cell Biol. 2 (4): 285–93. doi:10.1038/35067088. PMID 11283726.
Tsukita S, Furuse M (2003). "Claudin-based barrier in simple and stratified cellular sheets". Curr. Opin. Cell Biol. 14 (5): 531–6. doi:10.1016/S0955-0674(02)00362-9. PMID 12231346.
González-Mariscal L, Betanzos A, Nava P, Jaramillo BE (2003). "Tight junction proteins". Prog. Biophys. Mol. Biol. 81 (1): 1–44. doi:10.1016/S0079-6107(02)00037-8. PMID 12475568.
Berg M, Geisel A, Necheles H (1975). "The influence of carbenoxolone on steroid-induced ulcer and mucus secretion in the rat". The American journal of digestive diseases 20 (2): 134–7. doi:10.1007/BF01072339. PMID 1124737.
Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Mungall AJ, Palmer SA, Sims SK et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
Gerhard DS, Wagner L, Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

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