Bronidox

Bronidox
IUPAC name 5-Bromo-5-nitro-1,3-dioxane
Other names 5-Bromo-5-nitro-m-dioxane
Identifiers
CAS number	30007-47-7 Y=
PubChem	1807
ChemSpider	1741 Y
UNII	U184I9QBNM Y
EC number	250-001-7
Jmol-3D images	{{#if:O=[N+]([O-])C1(Br)COCOC1|Image 1
SMILES O=[N+]([O-])C1(Br)COCOC1
InChI InChI=1S/C4H6BrNO4/c5-4(6(7)8)1-9-3-10-2-4/h1-3H2 Y Key: XVBRCOKDZVQYAY-UHFFFAOYSA-N Y InChI=1/C4H6BrNO4/c5-4(6(7)8)1-9-3-10-2-4/h1-3H2 Key: XVBRCOKDZVQYAY-UHFFFAOYAG
Properties
Molecular formula	C4H6BrNO4
Molar mass	212.00 g mol−1
Appearance	White crystalline powder
Melting point	60 °C[1] 58.5−62 °C[2]
Solubility in water	insoluble
Hazards
R-phrases	R22 R38
S-phrases	S36
Main hazards	Toxic
LD50	590 mg/kg (mouse, oral) 455 mg/kg (rat, oral) 31 mg/kg (rat, ipr.) 2500 µg (mouse, skin) 2500 µg (rat, skin)[3]
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Bronidox, or 5-bromo-5-nitro-1,3-dioxane, is an antimicrobial chemical compound.

Bronidox causes inhibition of enzyme activity in bacteria.^[4]

Bronidox is corrosive to metals.^[5]

Uses

• Stabilizer
• Surfactant
• It is used in immunology for preserving antibodies and antisera in 0.1 - 0.5% concentration. It is used as preservative to avoid use of sodium azide.
• Bactericide. Very effective against yeast and fungi.
• Used in cosmetics since the mid-1970s as preservative for shampoos, foam bath, etc. Maximum concentration is 0.1%.
• Some users do not recommend use in preparations destined for in vivo or tissue culture work^[6]

See also

• Bronopol

References

External links

• http://www.chemicon.com/webfiles/MSDS/ECM711msds.pdf (Safety data sheet and first aid)
• http://www.fitzchem.com/mfg_cogniscare.shtml
• http://www.labodia.com/en/intrinsic_factor/material_safety_data_sheet.pdf