Bromazine

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Bromazine
Systematic (IUPAC) name
2-[(4-bromophenyl)-phenylmethoxy]-N,N-dimethylethanamine
Clinical data
MedlinePlus a682065
Legal status ?
Routes Oral
Pharmacokinetic data
Bioavailability High
Protein binding 96%
Metabolism Mostly hepatic (CYP-mediated), also renal
Half-life 1 to 4 hours
Identifiers
CAS number 1808-12-4 YesY 1808-12-4
ATC code R06AA01
PubChem CID 2444
DrugBank DB01237
ChemSpider 2350 YesY
UNII 202J683U97 YesY
ChEBI CHEBI:59177 YesY
ChEMBL CHEMBL1201245 N
Chemical data
Formula C17H20BrNO 
Mol. mass 334.251 g/mol
 N (what is this?)  (verify)

Bromazine (trade names Ambrodyl, Ambrodil and others), also known as bromodiphenhydramine, is an antihistamine and anticholinergic.[1] It is a halogenated form of diphenhydramine and in many respects is somewhat stronger than the parent compound.

References

  1. ↑ MacLaren, W. R.; Bruff, W. C.; Eisenberg, B. C.; Weiner, H.; Martin, W. H. (1955). "A clinical comparison of carbinoxamine maleate, tripelennamine hydrochloride, and bromodiphenhydramine hydrochloride in treating allergic symptoms". Annals of allergy 13 (3): 307–312. PMID 14377226. 
Aminoalkyl ethers
Substituted alkylamines
Substituted ethylenediamines
Phenothiazine derivatives
Piperazine derivatives
Others for systemic use
For topical use
Histaminergics
Receptor
  • Ungrouped: Belarizine
  • Efletirizine
  • Elbanizine
  • Flotrenizine
  • Medrylamine
  • Napactadine
  • Pibaxizine
  • Tagorizine
  • Trelnarizine
  • Trenizine
  • Vapitadine
Transporter
Enzyme
DAO
  • Inhibitors: Aminoguanidine
Others
Endogenous


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