Brian Christie (neuroscientist)

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For the television journalist, see Brian Christie.

Brian R. Christie (born 1964) is a Michael Smith Senior Scholar and an Associate Professor of Medicine and Neuroscience at The University of Victoria. He received his PhD in 1992 from the University of Otago before doing postdoctoral work with Daniel Johnston at Baylor College of Medicine and Terrence Sejnowski at the Salk Institute for Biological Studies, and then became Assistant Professor at the University of British Columbia.[1]

Research

Christie's research has shown that exercise promotes adult neurogenesis and synaptic plasticity in the hippocampus.[2][3]

This work has since progressed to show that exercise can have beneficial effects for the brains of animals that have been exposed to ethanol while in the womb, an animal model of fetal alcohol syndrome effects. His current work continues to examine how exercise can benefit the brain. He is part of the Island Medical Program and the Division of Medical Sciences, a joint venture of the University of British Columbia and the University of Victoria to increase the number of medical doctors being trained in Canada, and teaches neuroanatomy and problem-based learning (PBL) in this program .[1] His current research concentrates on how exercise generates new brain cells in people with Alzheimer’s Disease, stroke, Fetal Alcohol Syndrome Disorder (FASD) or Attention Deficit Hyperactivity Disorder (ADHD), particularly in the hippocampus.

Publications

His most cited peer-reviewed publications are:

  • Van Praag, H., Christie, B.R., Sejnowski, T.J., Gage, F.H. Running enhances neurogenesis, learning, and long-term potentiation in mice (1999) Proceedings of the National Academy of Sciences of the United States of America, 96 (23), pp. 13427–13431. Cited 744 times.
  • Johnston, D., Magee, J.C., Colbert, C.M., Christie, B.R. Active properties of neuronal dendrites (1996) Annual Review of Neuroscience, 19, pp. 165–186. Cited 313 times.
  • Seamans, J.K., Durstewitz, D., Christie, B.R., Stevens, C.F., Sejnowski, T.J. Dopamine D1/D5 receptor modulation of excitatory synaptic inputs to layer V prefrontal cortex neurons (2001) Proceedings of the National Academy of Sciences of the United States of America, 98 (1), pp. 301–306. Cited 176 times.
  • Farmer, J., Zhao, X., Van Praag, H., Wodtke, K., Gage, F.H., Christie, B.R. Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male sprague-dawley rats in vivo (2004) Neuroscience, 124 (1), pp. 71–79. Cited 166 times.

The h-index for his work is 27, that is, 27 articles cited 27 times or more.[citation needed]

Personal life

Christie lives in Saanich, British Columbia with his three children and wife.[citation needed]

References

  1. ↑ 1.0 1.1 "Island Medical Program profile". University of Victoria. Retrieved January 20, 2010. 
  2. ↑ "A Brain Besieged" The San Diego Union - Tribune - San Diego, Calif. by Scott LaFee Nov 17, 1999 abstract
  3. ↑ "Keeping fit can mean huge benefits for your brain: Neuron growth. by Katherine Dedyna, Canwest News Service, Monday, Feb. 2, 2009 National Post

External links

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