Bisphenol AF

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Bisphenol AF

IUPAC name 4-[1,1,1,3,3,3-Hexafluoro-2-(4-hydroxyphenyl)propan-2-yl]phenol
Other names Biphenol AF; Hexafluorobisphenol A; Hexafluorodiphenylolpropane; Bisphenol A hexafluoride; 4,4'-(Hexafluoroisopropylidene)diphenol; Hexafluoroacetone bisphenol A; 2,2-Bis(4-hydroxyphenyl)hexafluoropropane
Identifiers
Abbreviations	BPAF
CAS number	1478-61-1^Y
PubChem	73864
ChemSpider	66498^Y
Jmol-3D images	Image 1
SMILES C1=CC(=CC=C1C(C2=CC=C(C=C2)O)(C(F)(F)F)C(F)(F)F)O
InChI InChI=1S/C15H10F6O2/c16-14(17,18)13(15(19,20)21,9-1-5-11(22)6-2-9)10-3-7-12(23)8-4-10/h1-8,22-23H^Y Key: ZFVMWEVVKGLCIJ-UHFFFAOYSA-N^Y InChI=1/C15H10F6O2/c16-14(17,18)13(15(19,20)21,9-1-5-11(22)6-2-9)10-3-7-12(23)8-4-10/h1-8,22-23H Key: ZFVMWEVVKGLCIJ-UHFFFAOYAS
Properties
Molecular formula	C₁₅H₁₀F₆O₂
Molar mass	336.23 g mol⁻¹
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Bisphenol AF (BPAF) is a fluorinated organic compound related to bisphenol A in which the two methyl groups are replaced with trifluoromethyl groups.

Whereas BPA binds with human estrogen-related receptor gamma (ERR-γ), BPAF all but ignores ERR-γ. Instead, BPAF activates ERR-α and binds to and disables ERR-β.^[1]

References

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