Bis(trimethylsilyl)acetamide

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Bis(trimethylsilyl)acetamide
Identifiers
Abbreviations BSA
CAS number 10416-59-8 (E), chlorotimethylsilane YesY, 101660-04-2
PubChem 25248, 6913588 (E), 5372922 (Z), 12412242 (E), (tris(2H3)methyl), (tris(2H3)methyl), 44149724 (E), chlorotimethylsilane
ChemSpider 23581 YesY, 4523073 (E) YesY, 10516629 (Z) YesY
EC number 233-892-7
UN number 2920
MeSH N,O-bis(trimethylsilyl)acetamide
RTECS number AK3000000
Beilstein Reference 1306669
Jmol-3D images {{#if:CC(=N[Si](C)(C)C)O[Si](C)(C)CCC(O[Si](C)(C)C)=N[Si](C)(C)C|Image 1
Image 2
Properties
Molecular formula C8H21NOSi2
Molar mass 203.43 g mol−1
Appearance Liquid
Density 0.832 g cm-3
Boiling point 71 to 73 °C; 160 to 163 °F; 344 to 346 K (at 35mmHg)
Hazards
EU classification Corrosive (C)
R-phrases R10 R14 R22 R34
S-phrases S26 S36/37/39 S45
Related compounds
Related Amides Dimethylacetamide
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Bis(trimethylsilyl)acetamide (BSA) is used in analytical chemistry for the derivatisation[1] of compounds in analysis to increase their volatility.

It is also a good source of the trimethylsilyl group in protecting functional groups in chemistry.

See also

References

  1. Blau, Karl; J. M. Halket (1993). Handbook of Derivatives for Chromatography (2nd ed.). John Wiley & Sons. ISBN 0-471-92699-X. 
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