Bis(chloromethyl) ether
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| Bis(chloromethyl) ether | |
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| IUPAC name bis(chloromethyl) ether | |
| Other names bis-CME, chloro-(chloromethoxy)methane, oxybis[chloromethane] | |
| Identifiers | |
| CAS number | 542-88-1 |
| PubChem | 10967 |
| ChemSpider | 21106500 |
| EC number | 208-832-8 |
| KEGG | C19158  |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C2H4Cl2O |
| Molar mass | 114.96 g mol−1 |
| Melting point | −41.5 °C; −42.7 °F; 231.7 K |
| Boiling point | 106 °C; 223 °F; 379 K |
| Hazards | |
| Main hazards |  |
| Flash point | 38 °C; 100 °F; 311 K |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa) | |
| Infobox references | |
Bis(chloromethyl) ether is an organic compound with the chemical formula (CH2Cl)2O. It is one of the chloroalkyl ethers. This colorless liquid is used for chloromethylation of aromatic substrates. It is produced industrially from paraformaldehyde and a mixture of chlorosulfonic acid and sulfuric acid.[1]
Safety
Bis(chloromethyl) ether is carcinogenic.[2] It is one of 13 chemicals considered an OSHA-regulated occupational carcinogen.[3] Chronic exposure can increase the incidence of oat cell carcinoma, a type of lung cancer.[2]
References
- ↑ Wilhelm Heitmann, Günther Strehlke, Dieter Mayer “Ethers, Aliphatic” Ullmann's Encyclopedia of Industrial Chemistry 2002, Wiley-VCH, Weinheim. doi: 10.1002/14356007.a10_023
- ↑ 2.0 2.1 Integrated Risk Information System, United States Environmental Protection Agency
- ↑ NIOSH Pocket Guide to Chemical Hazards, Centers for Disease Control and Prevention
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