Beta-phosphoglucomutase
From Wikipedia, the free encyclopedia
| beta-phosphoglucomutase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 5.4.2.6 | ||||||||
| CAS number | 68651-99-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
| |||||||||
In enzymology, a beta-phosphoglucomutase (EC 5.4.2.6) is an enzyme that catalyzes the chemical reaction
- beta-D-glucose 1-phosphate
beta-D-glucose 6-phosphate
Hence, this enzyme has one substrate, beta-D-glucose 1-phosphate, and one product, beta-D-glucose 6-phosphate.
This enzyme belongs to the family of isomerases, specifically the phosphotransferases (phosphomutases), which transfer phosphate groups within a molecule. The systematic name of this enzyme class is beta-D-glucose 1,6-phosphomutase. This enzyme participates in starch and sucrose metabolism.
Structural studies
As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes 1LVH, 1O03, 1O08, 1Z4N, 1Z4O, and 1ZOL.
References
- Ben-Zvi R and Schramm M (1961). "A phosphoglucomutase specific for beta-glucose 1-phosphate". J. Biol. Chem. 236: 2186–2189.
- Boyer, P.D. (Ed.), The Enzymes, 3rd ed., vol. 6, 1972, p. 407-477.
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