Benzisothiazolinone

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Benzisothiazolinone
IUPAC name

1,2-benzisothiazol-3(2H)-one

Other names

Benzisothiazolinone, Benzisothiazolin-3-one, Benzisothiazolone

Identifiers
Abbreviations BIT
CAS number 2634-33-5 YesY
PubChem 17520
ChemSpider 16567 YesY
MeSH 1,2-benzisothiazoline-3-one
ChEBI CHEBI:167099 YesY
ChEMBL CHEMBL297304 YesY
Jmol-3D images Image 1
Properties
Molecular formula C7H5NOS
Molar mass 151.19 g mol−1
Appearance white powder
Melting point 158 °C [1]
Solubility in water 1 g/l
Hazards
R-phrases R22, R38, R41, R43, R50 [1]
S-phrases (S2), S24, S26, S37/39, S61 [1]
Main hazards Xn, N [1]
 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Benzisothiazolinone (BIT) is a widely used biocide and belongs to the group of isothiazolinones.

Usage

Benzisothiazolinone has a microbicide and a fungicide mode of action. It is used as a preservative in emulsion paints, varnishes, adhesives, washing agents, fuels and in the papermaking process. In paints, it is commonly used as a mixture with methylisothiazolinone. Typical concentrations in products are 200–400 ppm depending on the application area and the combination with other biocides. According to a study in Switzerland, 19% of the paints, varnishes and coatings contained BIT in 2000. The fraction in adhesives, sealants, plasters and fillers was 25%. [2]

Health hazards

It is a known human immune system toxicant, and also is classified as irritant for skin, eyes and lungs.[3] It is widely used as active ingredient of many home cleaning products.

References

  1. ↑ 1.0 1.1 1.2 1.3 Record of 1,2-Benzisothiazol-3(2H)-one in the GESTIS Substance Database from the IFA, accessed on 22 October 2007
  2. ↑ Reinhard et al.: "Preservation of products with MCI/MI in Switzerland". Contact Dermatitis. 2001 Nov;45(5):257-64. PMID 11722483
  3. ↑ EWG's Skin Deep Cosmetics Database

Literature

  • Wilfried Paulus: Directory of Microbicides for the Protection of Materials and Processes. Springer Netherland, Berlin 2006, ISBN 1-4020-4861-0.
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