Hydroxyamfetamine
From Wikipedia, the free encyclopedia
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|---|---|
| Systematic (IUPAC) name | |
| 4-(2-aminopropyl)phenol | |
| Clinical data | |
| Legal status | ℞ Prescription only |
| Routes | Topical (ocular) |
| Identifiers | |
| CAS number | 1518-86-1 |
| ATC code | None |
| PubChem | CID 3651 |
| ChemSpider | 3525 |
| ChEMBL | CHEMBL1546 |
| Chemical data | |
| Formula | C9H13NO |
| Mol. mass | 151.206 g/mol |
| SMILES
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Hydroxyamfetamine (INN; brand names Paredrine, Mycadrine, and Pedrolon) or hydroxyamphetamine (USAN, BAN), also known by the names oxamphetamine, norpholedrine, 4-hydroxyamphetamine, para-hydroxyamphetamine, and α-methyltyramine, is a sympathomimetic drug, that is, a drug that stimulates the sympathetic nervous system. When used in eye drops, it dilates the pupil. Hydroxyamfetamine is sold in combination with tropicamide under the brand name Paremyd. It occurs as a metabolite of amphetamine.
Once thought to be a human invention, hydroxyamfetamine is now known to occur as an alkaloid in plants including Acacia berlandieri.[1]
In 1944, the US Naval Submarine Medical Research Laboratory researched the use of Paredrine to improve adaptation to night vision in submarine personnel. A significant improvement in adaptation was shown in the 17 subjects they tested.[2]
See also
References
- ↑ Shulgin, Alexander (September 26, 2001). "Ask Dr. Shulgin Online: Acacias and Natural Amphetamine". Center for Cognitive Liberty & Ethics. Retrieved 2010-02-18.
- ↑ Verplanck, WS (1944). "The effects of paregrine on night vision performance.". US Naval Submarine Medical Research Laboratory Technical Report 42. Retrieved 2010-02-18.
External links
- p-Hydroxyamphetamine at the US National Library of Medicine Medical Subject Headings (MeSH)
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