Xylopropamine

Xylopropamine

Systematic (IUPAC) name
(±)-1-(3,4-dimethylphenyl)propan-2-amine
Clinical data
Legal status	℞ Prescription only
Routes	Oral
Identifiers
CAS number	14543-76-1 Y
ATC code	None
PubChem	CID 26727
ChemSpider	24901 N
Chemical data
Formula	C11H17N
Mol. mass	163.259 g/mol
SMILES c1c(ccc(c1C)C)CC(N)C
InChI InChI=1S/C11H17N/c1-8-4-5-11(6-9(8)2)7-10(3)12/h4-6,10H,7,12H2,1-3H3 N Key:ZSZUWPRERIPUBM-UHFFFAOYSA-N N
N (what is this?)  (verify)

Xylopropamine (Perhedrin, Esanin), also known as 3,4-dimethylamphetamine, is a stimulant drug of the phenethylamine and amphetamine classes which was developed and marketed as an appetite suppressant in the 1950s.^[1]

Xylopropamine was briefly sold as the sulfate salt, but it was not widely marketed. Other related amphetamine derivatives such as 2,4-dimethylamphetamine were also investigated for the same purpose, however these drugs had negative side effects such as high blood pressure and were not very successful, mainly due to the introduction of alternative drugs like phentermine which had similar efficacy but fewer side effects.

Xylopropamine was also reported as having analgesic^[2] and anti-inflammatory^[3] effects but its side effect profile resulted in it never being further developed for these applications.

See also

• Methamphetamine
• Dimethylamphetamine
• 3,4-Dimethylmethcathinone
• 4-Methylamphetamine
• 4-Methylmethamphetamine
• Indanylaminopropane

References