ZDHHC17
Palmitoyltransferase ZDHHC17 is an enzyme that contains a DHHC domain that in humans is encoded by the ZDHHC17 gene.[1][2][3]
Interactions
ZDHHC17 has been shown to interact with Huntingtin.[1][4]
References
- ^ a b Faber PW, Barnes GT, Srinidhi J, Chen J, Gusella JF, MacDonald ME (Oct 1998). "Huntingtin interacts with a family of WW domain proteins". Hum Mol Genet 7 (9): 1463–74. doi:10.1093/hmg/7.9.1463. PMID 9700202.
- ^ Goytain A, Hines RM, Quamme GA (Nov 2008). "Huntingtin-interacting proteins, HIP14 and HIP14L, mediate dual functions, palmitoyl acyltransferase and Mg2+ transport". J Biol Chem 283 (48): 33365–74. doi:10.1074/jbc.M801469200. PMC 2662264. PMID 18794299. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2662264.
- ^ "Entrez Gene: ZDHHC17 zinc finger, DHHC-type containing 17". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23390.
- ^ Singaraja, Roshni R; Hadano Shinji, Metzler Martina, Givan Scott, Wellington Cheryl L, Warby Simon, Yanai Anat, Gutekunst Claire-Anne, Leavitt Blair R, Yi Hong, Fichter Keith, Gan Lu, McCutcheon Krista, Chopra Vikramjit, Michel Jennifer, Hersch Steven M, Ikeda Joh-E, Hayden Michael R (Nov. 2002). "HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis". Hum. Mol. Genet. (England) 11 (23): 2815–28. doi:10.1093/hmg/11.23.2815. ISSN 0964-6906. PMID 12393793.
Further reading
- Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 6 (1): 63–70. doi:10.1093/dnares/6.1.63. PMID 10231032.
- Singaraja RR, Hadano S, Metzler M, et al. (2003). "HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis.". Hum. Mol. Genet. 11 (23): 2815–28. doi:10.1093/hmg/11.23.2815. PMID 12393793.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Matsuda A, Suzuki Y, Honda G, et al. (2003). "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.". Oncogene 22 (21): 3307–18. doi:10.1038/sj.onc.1206406. PMID 12761501.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
- Ducker CE, Stettler EM, French KJ, et al. (2005). "Huntingtin interacting protein 14 is an oncogenic human protein: palmitoyl acyltransferase.". Oncogene 23 (57): 9230–7. doi:10.1038/sj.onc.1208171. PMC 2908390. PMID 15489887. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2908390.
- Huang K, Yanai A, Kang R, et al. (2005). "Huntingtin-interacting protein HIP14 is a palmitoyl transferase involved in palmitoylation and trafficking of multiple neuronal proteins.". Neuron 44 (6): 977–86. doi:10.1016/j.neuron.2004.11.027. PMID 15603740.
- Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1356129.