| Yangonin | |
|---|---|
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4-Methoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]pyran-2-one |
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| Identifiers | |
| CAS number | 500-62-9 |
| PubChem | 5281575 |
| ChEMBL | CHEMBL1098658 |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C15H14O4 |
| Molar mass | 258.27 g mol−1 |
| Exact mass | 258.089209 |
| (verify) (what is: /?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Yangonin is one of the six major kavalactones found in the kava plant.[1]
Yangonin displays marked in vitro toxicity on human hepatocytes with approximately 40% reduction in viability based on an ethidium bromide assay. The predominant mode of cell death turned out to be apoptosis rather than necrosis. No significant changes were observed in glutathione levels.[2]
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