XPhos | |
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2-Dicyclohexylphosphino-2′,4′,6′-triisopropylbiphenyl |
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Other names
XPhos |
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Identifiers | |
CAS number | 564483-18-7 |
PubChem | 11155794 |
Properties | |
Molecular formula | C33H49P |
Molar mass | 476.72 |
Appearance | colorless solid |
Melting point |
187-190 °C |
Solubility in water | organic solvents |
(verify) (what is: / ?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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Infobox references |
XPhos is an organophosphorus compound derived from biphenyl. Its palladium complexes exhibit high activity for Buchwald-Hartwig amination reactions involving aryl chlorides and aryl tosylates. Both palladium and copper complexes of the compound exhibit high activity for the coupling of aryl halides and aryl tosylates with various amides.[1] The ligand has convenient handling characteristics since it is air-stable.[2]