VX-809

VX-809
Systematic (IUPAC) name
3-{6-{[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropanecarbonyl]amino}-3-methylpyridin-2-yl}benzoic acid
Clinical data
Pregnancy cat.  ?
Legal status Investigational
Identifiers
CAS number 936727-05-8 N
ATC code None
PubChem CID 16678941
Chemical data
Formula C24H18F2N2O5 
Mol. mass 452.407 g/mol
SMILES eMolecules & PubChem
 N(what is this?)  (verify)

VX-809 is an experimental drug for the treatment of cystic fibrosis. The drug is designed to be effective in patients that have the F508del mutation in the cystic fibrosis transmembrane conductance regulator (CFTR), the defective protein that causes the disease. F508del, meaning that the amino acid phenylalanine in position 508 is missing, is found in about 90% of cystic fibrosis patients.[1]

See also

References

  1. ^ Merk; Schubert-Zsilavecz. (in German)Pharmazeutische Zeitung 156 (37): 24–27.