Users' Guides to the Medical Literature

Users’ Guides to the Medical Literature  
Author(s) Gordon Guyatt, Drummond Rennie
Subject(s) Medicine
Publisher American Medical Association Press
Publication date 2001

The Users’ Guides to the Medical Literature is a series of articles originally published in the Journal of the American Medical Association,[1] now rewritten and compiled in a textbook format.[2] The guides provide practical, clinician-friendly advice on all aspects of evidence-based medicine.

Contents

As articles

During the late 1970s a group of clinical epidemiologists at McMaster University including Dr. David Sackett prepared a series of articles to assist clinicians interpreting clinical research. These articles, introducing the term "critical appraisal", appeared in the Canadian Medical Association Journal beginning in 1981 and were immensely popular.

In 1990 Dr. Gordon Guyatt introduced the term "evidence-based medicine" to describe a paradigm shift in medical practice that stressed the role of rigorous, systematic evidence from clinical research in conjunction with patients’ values and preferences in clinical decision-making.[3] A group of academic physicians subsequently formed the first international Evidence-based Medicine Working Group and published an article expanding on the concept of evidence-based medicine.[4]

The Evidence-based Medicine Working Group decided to build on the popular series in the Canadian Medical Association Journal by creating a more practical approach to applying the medical literature to clinical practice. Championed by Dr. Drummond Rennie, an editor of the Journal of the American Medical Association, the result was the Users' Guides. The guides originally consisted of 25 topics, covered in a series of 32 articles published in the Journal of the American Medical Association between 1993 and 2000, describing approaches to different types of medical questions and the study designs that may answer them.[1]

The complete list is as follows:

Barratt, A. et al., 1999. Users’ Guides to the Medical Literature: XVII. How to Use Guidelines and Recommendations About Screening. JAMA, 281(21), pp.2029-2034. Available at: http://jama.ama-assn.org/cgi/doi/10.1001/jama.281.21.2029

Bucher, H.C. et al., 1999. Users’ Guides to the Medical Literature: XIX. Applying Clinical Trial Results; A. How to Use an Article Measuring the Effect of an Intervention on Surrogate End Points. JAMA, 282(8), pp.771-778. Available at: http://jama.ama-assn.org/cgi/doi/10.1001/jama.282.8.771.

Dans, A.L. et al., 1998. Users’ Guides to the Medical Literature: XIV. How to Decide on the Applicability of Clinical Trial Results to Your Patient. JAMA, 279(7), pp.545-549. Available at: http://jama.ama-assn.org/cgi/doi/10.1001/jama.279.7.545

Drummond, M.F. et al., 1997. Users’ guides to the medical literature. XIII. How to use an article on economic analysis of clinical practice. A. Are the results of the study valid? Evidence-Based Medicine Working Group. JAMA, 277(19), pp.1552-1557. Available at: http://jama.ama-assn.org.

GH, G. et al., 1995. Users’ guides to the medical literature, IX: a method for grading health care recommendations. JAMA, 274, pp.1800-1804.

Giacomini, M.K. & Cook, D.J., 2000. Users’ Guides to the Medical Literature: XXIII. Qualitative Research in Health Care A. Are the Results of the Study Valid? JAMA, 284(3), pp.357-362. Available at: http://jama.ama-assn.org/cgi/doi/10.1001/jama.284.3.357

Giacomini, M.K. & Cook, D.J., 2000. Users’ Guides to the Medical Literature: XXIII. Qualitative Research in Health Care B. What Are the Results and How Do They Help Me Care for My Patients? JAMA, 284(4), pp.478-482. Available at: http://jama.ama-assn.org/cgi/doi/10.1001/jama.284.4.478.

Guyatt, G., Sackett, D. & Cook, D., 1993. Users’ guides to the medical literature, II: how to use an article about therapy or prevention, A: are the results of the study valid? JAMA, 270, pp.2598-2601.

Guyatt, G., Sackett, D. & Cook, D., 1994. Users’ guides to the medical literature, II: how to use an article about therapy or prevention, B: what were the results and will they help me in caring for my patients? JAMA, 271, pp.59-63.

Guyatt, G.H. & Rennie, D., 1993. Users’ guides to the medical literature. JAMA, 270(17), pp.2096-2097. Available at: http://jama.ama-assn.org.

Guyatt, G.H. et al., 2000. Users’ Guides to the Medical Literature: XXV. Evidence-Based Medicine: Principles for Applying the Users' Guides to Patient Care. JAMA, 284(10), pp.1290-1296. Available at: http://jama.ama-assn.org/cgi/doi/10.1001/jama.284.10.1290.

Guyatt, G.H. et al., 1997. Users’ guides to the medical literature. XII. How to use articles about health-related quality of life. Evidence-Based Medicine Working Group. JAMA, 277(15), pp.1232-1237. Available at: http://jama.ama-assn.org. Guyatt, G.H. et al., 1999. Users’ Guides to the Medical Literature: XVI. How to Use a Treatment Recommendation. JAMA, 281(19), pp.1836-1843. Available at: http://jama.ama-assn.org/cgi/doi/10.1001/jama.281.19.1836

Hayward, R.S. et al., 1995. Users’ guides to the medical literature. VIII. How to use clinical practice guidelines. A. Are the recommendations valid? The Evidence-Based Medicine Working Group. JAMA, 274(7), pp.570-574. Available at: http://jama.ama-assn.org.

Hunt, D.L., Jaeschke, R.Z. & McKibbon, K.A., 2000. Users’ Guides to the Medical Literature: XXI. Using Electronic Health Information Resources in Evidence-Based Practice. JAMA, 283(14), pp.1875-1879. Available at: http://jama.ama-assn.org/cgi/doi/10.1001/jama.283.14.1875

Jaeschke, R.Z., Guyatt, G.H. & Sackett, D.L., 1994. Users’ guides to the medical literature. III. How to use an article about a diagnostic test. A. Are the results of the study valid? Evidence-Based Medicine Working Group. JAMA, 271(5), pp.389-391. Available at: http://jama.ama-assn.org.

Jaeschke, R.Z., Guyatt, G.H. & Sackett, D.L., 1994. Users’ guides to the medical literature. III. How to use an article about a diagnostic test. B. What are the results and will they help me in caring for my patients? The Evidence-Based Medicine Working Group. JAMA, 271(9), pp.703-707. Available at: http://jama.ama-assn.org.

Laupacis, A et al., 1994. Users’ guides to the medical literature. V. How to use an article about prognosis. Evidence-Based Medicine Working Group. JAMA, 272(3), pp.234-237. Available at: http://jama.ama-assn.org.

Levine, M. et al., 1994. Users’ guides to the medical literature. IV. How to use an article about harm. Evidence-Based Medicine Working Group. JAMA, 271(20), pp.1615-1619. Available at: http://jama.ama-assn.org.

McAlister, F.A. et al., 1999. Users’ Guides to the Medical Literature: XIX. Applying Clinical Trial Results; B. Guidelines for Determining Whether a Drug Is Exerting (More Than) a Class Effect. JAMA, 282(14), pp.1371-1377. Available at: http://jama.ama-assn.org/cgi/doi/10.1001/jama.282.14.1371

McAlister, F.A. et al., 2000. Users’ Guides to the Medical Literature: XX. Integrating Research Evidence With the Care of the Individual Patient. JAMA, 283(21), pp.2829-2836. Available at: http://jama.ama-assn.org/cgi/doi/10.1001/jama.283.21.2829

McGinn, T.G. et al., 2000. Users’ Guides to the Medical Literature: XXII: How to Use Articles About Clinical Decision Rules. JAMA, 284(1), pp.79-84. Available at: http://jama.ama-assn.org/cgi/doi/10.1001/jama.284.1.79

Naylor, C.D. & Guyatt, G.H., 1996. Users’ guides to the medical literature. X. How to use an article reporting variations in the outcomes of health services. The Evidence-Based Medicine Working Group. JAMA, 275(7), pp.554-558. Available at: http://jama.ama-assn.org.

Naylor, C.D. & Guyatt, G.H., 1996. Users’ guides to the medical literature. XI. How to use an article about a clinical utilization review. Evidence-Based Medicine Working Group. JAMA, 275(18), pp.1435-1439. Available at: http://jama.ama-assn.org.

Oxman, A.D., Cook, D.J. & Guyatt, G.H., 1994. Users’ guides to the medical literature. VI. How to use an overview. Evidence-Based Medicine Working Group. JAMA, 272(17), pp.1367-1371. Available at: http://jama.ama-assn.org.

O’Brien, B.J. et al., 1997. Users’ guides to the medical literature. XIII. How to use an article on economic analysis of clinical practice. B. What are the results and will they help me in caring for my patients? Evidence-Based Medicine Working Group. JAMA, 277(22), pp.1802-1806. Available at: http://jama.ama-assn.org.

Randolph, A.G. et al., 1999. Users’ Guides to the Medical Literature: XVIII. How to Use an Article Evaluating the Clinical Impact of a Computer-Based Clinical Decision Support System. JAMA, 282(1), pp.67-74. Available at: http://jama.ama-assn.org/cgi/doi/10.1001/jama.282.1.67

Richardson, W.S. & Detsky, A.S., 1995. Users’ guides to the medical literature. VII. How to use a clinical decision analysis. A. Are the results of the study valid? Evidence-Based Medicine Working Group. JAMA, 273(16), pp.1292-1295. Available at: http://jama.ama-assn.org.

Richardson, W.S. & Detsky, A.S., 1995. Users’ guides to the medical literature. VII. How to use a clinical decision analysis. B. What are the results and will they help me in caring for my patients? Evidence Based Medicine Working Group. JAMA, 273(20), pp.1610-1613. Available at: http://jama.ama-assn.org.

Richardson, W.S. et al., 1999. Users’ Guides to the Medical Literature: XV. How to Use an Article About Disease Probability for Differential Diagnosis. JAMA, 281(13), pp.1214-1219. Available at: http://jama.ama-assn.org/cgi/doi/10.1001/jama.281.13.1214

Richardson, W.S. et al., 2000. Users’ Guides to the Medical Literature: XXIV. How to Use an Article on the Clinical Manifestations of Disease. JAMA, 284(7), pp.869-875. Available at: http://jama.ama-assn.org/cgi/doi/10.1001/jama.284.7.869

Wilson, M.C. et al., 1995. Users’ guides to the Medical Literature. VIII. How to use clinical practice guidelines. B. what are the recommendations and will they help you in caring for your patients? The Evidence-Based Medicine Working Group. JAMA, 274(20), pp.1630-1632. Available at: http://jama.ama-assn.org.

As books

Dr. Guyatt and Dr. Rennie edited the articles and compiled them to form a book titled Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice.[2] The Users' Guides now come in two book versions. The Essentials introduces the concepts of evidence-based medicine (EBM), with which every practicing clinician should be familiar. The Manual provides a comprehensive, in-depth exploration of the EBM concepts for clinicians seeking a deeper understanding of EBM, or for those who wish to role-model and teach EBM.

The books teach a systematic approach to reading and applying the medical literature to individual patient care. It focuses on three questions: 1. Whether new information is likely to be true, 2. What the information says about patient care, and 3. How the information can be used. To demonstrate the clinical relevance of the suggested approach, each section begins with a practical clinical scenario. The chapter is then structured around identifying the best available evidence and applying the three key questions to the evidence, in the context of the clinical scenario. Each chapter concludes with a resolution of the scenario.

Most of the book chapters are based on specific types of clinical questions, including questions of therapy, harm, diagnosis, and prognosis. Other chapters deal with general skills that are important for all clinical questions, such as “Finding the Evidence”, “Summarizing the Evidence”, and “Moving From Evidence to Action”. This highly structured format allows readers to quickly locate the information they need to incorporate EBM into their practice. While readers will enjoy reading the book from cover to cover, they need not do so – the Users’ Guides functions equally well as a reference book to be called upon as needed.

The Users’ Guides is also available in Web-based formats for clinicians who prefer electronic material. The website includes a large number of additional aids for the practice of EBM.

Readers of the British Medical Journal have ranked evidence-based medicine as one of the ten most important medical breakthroughs of the twentieth century.[5] Clinicians who wish to understand the medical literature and use it effectively in solving patient problems must have a firm understanding of the principles of EBM. The Essentials Users’ Guides provides the optimal introduction to familiarize clinicians with the tools needed to practice EBM.

References

  1. ^ a b Guyatt GH, Rennie D. Users' guides to the medical literature. JAMA. 1993; 270:2096-2097.
  2. ^ a b Users' Guides to the Medical Literature: A Manual of Evidence-Based Clinical Practice. Guyatt GH, Rennie D, eds. Chicago, IL: AMA Press; 2002.
  3. ^ Guyatt GH. Evidence-based medicine. ACP Journal Club. 1991;114:A-16.
  4. ^ Evidence-Based Medicine Working Group. Evidence-based medicine: a new approach to the teaching of medicine. JAMA. 1992;268:2420-2425.
  5. ^ Medical Milestones 2007. BMJ. 334:s2.

External links