UMB66

UMB66
Systematic (IUPAC) name
3-chloropropionic acid
Clinical data
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 107-94-8
ATC code  ?
Chemical data
Formula C3H5ClO2 
Mol. mass 108.52 g/mol
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3-Chloropropanoic acid or UMB66 is a drug used in scientific research. It is structurally related to GHB and binds to the GHB receptor, but has no affinity for GABA receptors.[1] It is also an active ingredient in some herbicide blends.[2] Overdose may cause unconsciousness and/or convulsions.[3]

Density 1,27g/cm3

appearance white to off white crystalline powder

melting point 38-41 °C

boiling point 203-205 °C

flash point 125 °C

References

  1. ^ Alba T. Macias, R. Jason Hernandez, Ashok K. Mehta, Alexander D. MacKerell Jr., Maharaj K. Ticku, Andrew Coop. 3-Chloropropanoic acid (UMB66): a ligand for the gamma-hydroxybutyric acid receptor lacking a 4-hydroxyl group. Bioorganic & Medicinal Chemistry. 1997 Jan.
  2. ^ Ng , Hong Jing and Ab. Wahab, Roswanira and Ronald A. , Cooper and Huyop, Fahrul. Degradation Of Herbicide (3-Chloropropionic Acid) By Bacterial Dehalogenases. Proc. KUSTEM 4th Annual Seminar 2005. pp. 586-590.
  3. ^ Chemical Data Sheet for 3-CHLOROPROPIONIC ACID: http://cameochemicals.noaa.gov/chemical/10304
Receptor
ligands
1,4-BD • 4-Methyl-GHB • GABOB • GBL • GHB • GHV • GVL • NCS-356 • NCS-435 • T-HCA • UMB66 • UMB68 • UMB72 • UMB86; Benzamides: Amisulpride • Sulpiride • Sultopride