UCO

UCO may refer to:

In education

• University of Central Oklahoma (Edmond, Oklahoma, USA)
• University of California Observatories, a multi-campus astronomical research unit of the University of California
• Catholic University of the West
• Universidad Católica de Oriente

IRC

• Abbreviation for Unknown Chatting Object

In music

• UCO, female vocalist of the Japanese band Funta

Other

• Unequal crossing over, a DNA mutation mechanism
• University Christian Outreach, an ecumenical, charismatic Christian organization on college campuses.