| Systematic (IUPAC) name | |
|---|---|
| N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl)-1-oxaspiro[4.5]dec-8-yl]acetamide | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 96744-75-1 |
| ATC code | None |
| PubChem | CID 105104 |
| IUPHAR ligand | 1655 |
| ChemSpider | 94828 |
| ChEMBL | CHEMBL440765 |
| Chemical data | |
| Formula | C22H32N2O2 |
| Mol. mass | 356.50 g/mol |
| SMILES | eMolecules & PubChem |
U-69,593 is a drug which acts as a potent and selective κ1-opioid receptor agonist.[1][2][3] In animal studies it has been shown to produce antinociception,[1][4][5] anti-inflammation,[6] anxiolysis (at low doses),[7][8][9] respiratory depression,[5] and diuresis,[10] while having little effect on gastrointestinal motility.[1] It also inhibits the peripheral, though not central secretion of oxytocin and vasopressin in rats.[11][12]
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