Triazole
Triazole (Htrz) refers to either one of a pair of isomeric chemical compounds with molecular formula C2H3N3, having a five-membered ring of two carbon atoms and three nitrogen atoms.
The two isomers are:
Derivatives
The triazole antifungal drugs include fluconazole, isavuconazole, itraconazole, voriconazole, pramiconazole, and posaconazole.
The triazole plant protection fungicides include epoxiconazole, triadimenol, propiconazole, metconazole, cyproconazole, tebuconazole, flusilazole and paclobutrazol.
Importance in agriculture
Due to spreading resistance of plant pathogens towards fungicides of the strobilurin class,[1] control of fungi such as Septoria tritici or Gibberella zeae[2] relies heavily on triazoles.
Related heterocycles
- Imidazole, an analog with two nonadjacent nitrogen atoms
- Pyrazole, an analog with two adjacent nitrogen atoms
- Tetrazole, an analog with four nitrogen atoms
External links
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topical: Bifonazole, Butoconazole, Clomidazole, Clotrimazole#, Croconazole, Econazole, Fenticonazole, Ketoconazole, Isoconazole, Miconazole#, Neticonazole, Omoconazole, Oxiconazole, Sertaconazole, Sulconazole, Tioconazole |
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Triazoles
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References
- ^ Gisi U, Sierotzki H,Cook A, McCaffery A (2002): Mechanisms influencing the evolution of resistance to Qo inhibitor fungicides. Pest Management Science 58: 859–867. [1]
- ^ Klix MB, Verreet J-A, Beyer M (2007): Comparison of the declining triazole sensitivity of Gibberella zeae and increased sensitivity achieved by advances in triazole fungicide development. Crop Protection 26:683-690. [2]