Tombusvirus

Tombusvirus
Virus classification
Group: Group IV ((+)ssRNA)
Family: Tombusviridae
Genus: Tombusvirus

The genus Tombusvirus are part of the family Tombusviridae and are members of group IV of the Baltimore classification of viruses. The genomes consist of positive sense single-stranded RNA with a genome size of 4800 nucleotides. The virions are non-enveloped with a diameter of 30 nm and have an isometric nucleocapsid (icosahedral; T=3). These virions have a regular surface structure and are composed of 17% nucleic acid.

This genera of viruses include the tomato bushy stunt virus (hence the name).

The virus uses the cis-regulatory elements, Tombus virus defective interfering (DI) RNA region 3 and Tombusvirus 5' UTR to control expression of defective interfering RNAs and viral RNA replication.[1][2]

References

  1. ^ Ray D, White KA (2003). "An internally located RNA hairpin enhances replication of Tomato bushy stunt virus RNAs". J. Virol. 77 (1): 245–57. doi:10.1128/JVI.77.1.245-257.2003. PMC 140596. PMID 12477830. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=140596. 
  2. ^ Wu B, Vanti WB, White KA (2001). "An RNA domain within the 5' untranslated region of the tomato bushy stunt virus genome modulates viral RNA replication". J. Mol. Biol. 305 (4): 741–56. doi:10.1006/jmbi.2000.4298. PMID 11162089. 

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