Ticlatone

Ticlatone

Systematic (IUPAC) name
6-chloro-1,2-benzothiazol-3(2H)-one
Clinical data
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	70-10-0
ATC code	D01AE08
PubChem	CID 6258
UNII	BHW384Q9GI^Y
KEGG	D06139^Y
Synonyms	Landromil
Chemical data
Formula	C₇H₄Cl N O S
Mol. mass	185.63 g/mol
Physical data
Melt. point	270–273 °C (518–523 °F)
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Ticlatone is an antifungal.

Antifungals (D01 and J02)

Wall/
membrane

Ergosterol
inhibitors

Azoles
(lanosterol 14
alpha-demethylase inhibitors)

Imidazoles	topical: Bifonazole, Butoconazole, Clomidazole, Clotrimazole^#, Croconazole, Econazole, Fenticonazole, Ketoconazole, Isoconazole, Miconazole^#, Neticonazole, Omoconazole, Oxiconazole, Sertaconazole, Sulconazole, Tioconazole

Triazoles	topical: (Fluconazole^#, Fosfluconazole, Terconazole) systemic: (Fluconazole, Hexaconazole, Isavuconazole^†, Itraconazole, Posaconazole, Voriconazole) unknown: (Albaconazole)

Thiazoles	topical: (Abafungin)

Polyene antimycotics
(ergosterol binding)

topical: (Hamycin, Natamycin, Nystatin^#)
systemic: (Amphotericin B^#, Hamycin)

Allylamines
(squalene monooxygenase
inhibitors)

topical: (Amorolfine, Butenafine, Naftifine, Terbinafine)
systemic: (Terbinafine)

β-glucan synthase
inhibitors

echinocandins (Anidulafungin, Caspofungin, Micafungin)

Intracellular

Pyrimidine analogues/ Thymidylate synthase inhibitors	Flucytosine^#

Mitotic inhibitors	Griseofulvin^#

Others

Bromochlorosalicylanilide • Methylrosaniline • Tribromometacresol • Undecylenic acid • Polynoxylin • Chlorophetanol • Chlorphenesin • Ticlatone • Sulbentine • Ethyl hydroxybenzoate • Haloprogin • Salicylic acid • Selenium sulfide^# • Ciclopirox • Amorolfine • Dimazole • Tolnaftate • Tolciclate • Sodium thiosulfate^# • Whitfield's ointment^# • Potassium iodide^# • Taurolidine

Tea tree oil • citronella oil • lemon grass • orange oil • patchouli • lemon myrtle

PCP: Pentamidine • Dapsone • Atovaquone

^#WHO-EM. ^‡Withdrawn from market. Clinical trials: ^†Phase III. ^§Never to phase III

M: MYC

fung, clas

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drug (fung)