Tetrahydroharman

Tetrahydroharman
Preferred IUPAC name

1-Methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
Systematic name

1-Methyl-1H,2H,3H,4H,9H-pyrido[3,4-b]indole
Other names

Elaeagnine

Methtryptoline

Tetrahydroharmane
Identifiers
CAS number 525-40-6, 23844-21-5 (1S), 2254-36-6 (1R), 2506-10-7
PubChem 91522 () Y, 704991 (1S) Y
ChemSpider 82643 Y, 614612 (1S) Y, 390581 (1R) Y
EC number 219-711-4
KEGG C09089
MeSH Tetrahydroharmane
ChEBI CHEBI:311872
Jmol-3D images Image 1
Properties
Molecular formula C12H14N2
Molar mass 186.25296 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Tetrahydroharman(e), also known as 1-methyl-1,2,3,4-tetrahydro-β-carboline, is a general name for one of two isomers:

  1. (1S)-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
  2. Calligonine ((1R)-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole)

Calligonine is a major alkaloid constituent of the roots of Calligonum minimum and the bark of Elaeagnus angustifolia. When taken internally, it has the effect of substantially lowering blood pressure for an extended period of time, similar to reserpine.

References

See also