Terizidone

Terizidone

Systematic (IUPAC) name
4,4'-{1,4-phenylenebis[(E)methylylidenenitrilo]}diisoxazolidin-3-one
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	25683-71-0^Y
ATC code	J04AK03
PubChem	CID 65720
ChemSpider	59144^Y
UNII	1199LEX5N8^Y
KEGG	D07247^Y
Synonyms	4-[({4-[N-(3-oxo-1,2-oxazolidin-4-yl)carboximidoyl]phenyl}methylidene)amino]-1,2-oxazolidin-3-one
Chemical data
Formula	C₁₄H₁₄N₄O₄
Mol. mass	302.286 g/mol
SMILES	eMolecules & PubChem
InChI InChI=1S/C14H14N4O4/c19-13-11(7-21-17-13)15-5-9-1-2-10(4-3-9)6-16-12-8-22-18-14(12)20/h1-6,11-12H,7-8H2,(H,17,19)(H,18,20)/b15-5+,16-6+^Y Key:ODKYYBOHSVLGNU-IAGONARPSA-N^Y
Y(what is this?) (verify)

Terizidone is a drug used in the treatment of tuberculosis.^[1]

References

^ "[Tolerability to terizidone (TZ) in the treatment of pulmonary tuberculosis in dialyzed patients]". Minerva Med. 82 (7-8): 477–81. 1991. PMID 1922892.

Rifamycins/ RNA polymerase inhibitor	Rifampicin^# • Rifabutin • Rifapentine

Antifolates/DSI	Dapsone^# • Acedapsone • Aldesulfone sodium

ASA	4-Aminosalicylic acid^# (Calcium aminosalicylate, Sodium aminosalicylate)

Aminoglycosides	Amikacin^# • Capreomycin^# • Kanamycin^# • Streptomycin^#

Oxazolidone	Linezolid

Peptidoglycan layer	Alanine analogue: Cycloserine^#

Arabinogalactan layer	Ethylenediamine/arabinosyltransferase inhibitor: Ethambutol^# SQ109^†

Mycolic acid layer	Hydrazides/mycolic acid synth. inhibition: Isoniazid^# Thiocarbamides: Ethionamide^# • Prothionamide • Thiocarlide

Other/unknown

phenazine (Clofazimine)^# • pyrazine (Pyrazinamide^#, Morinamide) • isoxazole (Terizidone) • R207910/TMC207^†

Combinations

bact (clas)

gr+f/gr+a(t)/gr-p(c)/gr-o

drug(J1p, w, n, m, vacc)